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Gene Expression Data
Assay Details
Assay
Reference: J:104893 Seo KW, et al., Targeted disruption of the DM domain containing transcription factor Dmrt2 reveals an essential role in somite patterning. Dev Biol. 2006 Feb 1;290(1):200-10
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6359422
Gene symbol: Lama1
Gene name: laminin, alpha 1
Results
Specimen 5A/E: embryonic day 10.5; Dmrt2tm1Rjo/Dmrt2+ (more )
Note: Triple labeled: red - Lama1; green - Des (assay MGI:6359421); blue - DAPI.
Structure Level Pattern Image Note
TS17: dermomyotome Present Regionally restricted 5E , 5A Expression in sheath surrounding dermomyotome.
TS17: neural tube Present 5A , 5E
Specimen 5B/F: embryonic day 10.5; Dmrt2tm1Rjo/Dmrt2tm1Rjo (more )
Note: Triple labeled: red - Lama1; green - Des (assay MGI:6359421); blue - DAPI.
Structure Level Pattern Image Note
TS17: dermomyotome Absent 5F , 5B Expression reduced or absent in dermomyotomal area.
TS17: neural tube Present 5B , 5F Expression in not changed compared with normal.
Specimen 5G/K: embryonic day 10.5; Dmrt2tm1Rjo/Dmrt2+ (more )
Note: Triple labeled: red - Lama1; green - Des (assay MGI:6359421); blue - DAPI.
Structure Level Pattern Image Note
TS17: dermomyotome Present Regionally restricted 5K , 5G Expression surrounding dermomyotome/myotome complex.
Specimen 5H/L: embryonic day 10.5; Dmrt2tm1Rjo/Dmrt2tm1Rjo (more )
Note: Triple labeled: red - Lama1; green - Des (assay MGI:6359421); blue - DAPI.
Structure Level Pattern Image Note
TS17: myotome Trace 5L , 5H Expression significantly reduced. Very low expression in mytome.
TS17: dermatome Absent 5L , 5H
Specimen 5O: embryonic day 10.5; Dmrt2tm1Rjo/Dmrt2+ (more )
Structure Level Pattern Image Note
TS17: dermomyotome Present Regionally restricted 5O Expression surrounding dermomyotome/myotome complex.
Specimen 5P: embryonic day 10.5; Dmrt2tm1Rjo/Dmrt2tm1Rjo (more )
Structure Level Pattern Image Note
TS17: myotome Trace 5P Expression significantly reduced. Very low expression in mytome.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory