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Gene Expression Data
Assay Details
Assay
Reference: J:29590 Friedman GC, et al., Tissue plasminogen activator mRNA expression in granule neurons coincides with their migration in the developing cerebellum. J Comp Neurol. 1995 Oct 2;360(4):658-70
Assay type: RNA in situ
MGI Accession ID: MGI:6358852
Gene symbol: Plat
Gene name: plasminogen activator, tissue
Probe: pK2C3z
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 3A: embryonic day 17.0 (more )
Structure Level Pattern Image Note
TS25: cerebellum Moderate 3A
TS25: deep cerebellar nucleus Moderate 3A
TS25: cerebral aqueduct Strong Regionally restricted 3A Expression is in the neuroepithelial layer in the basal plate.
TS25: hindbrain floor plate Strong Regionally restricted 3A Expression is in the floor of the 4th ventricle.
TS25: glomerular tuft Strong 3A

Specimen 3B: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: cerebellum molecular layer Present Regionally restricted 3B Expression is in a thin layer below the external granule layer.
TS27: brain meninges Present 3B
TS27: main olfactory bulb Present 3B
TS27: mammillary body Present 3B

Specimen 3C: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Present 3C
TS28: cerebellum internal granule cell layer Present 3C
TS28: cerebellum molecular layer Present 3C
TS28: cerebellum external granule cell layer Absent 3C

Specimen 3D: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Strong 3D
TS28: cerebellum internal granule cell layer Strong 3D

Specimen 3E: postnatal day 21 (more )
Structure Level Pattern Image Note
TS28: cerebellum internal granule cell layer Present 3E
TS28: dentate gyrus Present 3E

Specimen 3F: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cerebellum internal granule cell layer Present 3F
TS28: dentate gyrus Present 3F

Specimen 4A: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Strong 4A
TS28: cerebellum internal granule cell layer Strong 4A

Specimen 5A: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Present Regionally restricted 5A Expression is in small elongated cells.
TS28: cerebellum molecular layer Present Regionally restricted 5A Expression is in small elongated cells and at the external granule/molecular interface.
TS28: meninges Present Single cells 5A
TS28: cerebellum external granule cell layer Absent 5A

Specimen 5B: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Present 5B
TS28: cerebellum molecular layer Present Regionally restricted 5B Expression is in small elongated cells and at the external granule/molecular interface.
TS28: cerebellum internal granule cell layer Weak Diffuse 5B Expression is light and diffuse with accumulation at the interface.
TS28: cerebellum external granule cell layer Absent 5B

Specimen 6A: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cerebellum internal granule cell layer Weak Diffuse 6A
TS28: cerebellum molecular layer Weak 6A The amount of expressing cells decreased to 8.7% from that seen at P7.

Specimen 7 top: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Strong 7_top
TS28: cerebellum molecular layer Present 7_top

Specimen 8: postnatal day 10 (more )
Note: Double labeled: silver grains - Plat; fluorescence - Rbfox3 (assay MGI:6358853).
Structure Level Pattern Image Note
TS28: cerebellum molecular layer Present Single cells 8_top , 8_bottom

Specimen 9: postnatal day 10 (more )
Note: Double labeled: silver grains - Plat; fluorescence - Gfap (assay MGI:6359445).
Structure Level Pattern Image Note
TS28: cerebellum molecular layer Present Single cells 9_bottom , 9_top


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory