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Gene Expression Data
Assay Details
Assay
Reference: J:259672 Peng J, et al., Loss of Dcc in the spinal cord is sufficient to cause a deficit in lateralized motor control and the switch to a hopping gait. Dev Dyn. 2018 Apr;247(4):620-629
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6358766
Gene symbol: Dcc
Gene name: DCC netrin 1 receptor
Antibody: anti-DCC (A-20): sc-6535
Detection system: Alexa Fluor 488
Results
Specimen 1D: embryonic day 11.5; Dcctm1Nki/Dcc+, Tg(Hoxb8-cre)1403Uze/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: future spinal cord Present 1D
Specimen 1E: embryonic day 11.5; Dcctm1Nki/Dcctm1Nki, Tg(Hoxb8-cre)1403Uze/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: future spinal cord Present 1E No changes in expession levels or pre-crossing commissural axon trajectory in rostral spinal cord.
Specimen 1H/H': embryonic day 11.5; Dcctm1Nki/Dcc+, Tg(Hoxb8-cre)1403Uze/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: future spinal cord Present 1H' , 1H
Specimen 1I/I': embryonic day 11.5; Dcctm1Nki/Dcctm1Nki, Tg(Hoxb8-cre)1403Uze/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: future spinal cord Trace 1I' , 1I Expression drastically reduced in intermediate parts of spinal cord.
Specimen 1L: embryonic day 11.5; Dcctm1Nki/Dcc+, Tg(Hoxb8-cre)1403Uze/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: future spinal cord Present 1L
Specimen 1M: embryonic day 11.5; Dcctm1Nki/Dcctm1Nki, Tg(Hoxb8-cre)1403Uze/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: future spinal cord Trace 1M Expression drastically reduced in caudal parts of spinal cord.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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09/30/2025
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