Gene Expression Data
Assay Details
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Assay
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Reference:
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J:78745
Bishop KM, et al., Distinct actions of Emx1, Emx2, and Pax6 in regulating the specification of areas in the developing neocortex. J Neurosci. 2002 Sep 1;22(17):7627-38
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:6358650
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Gene symbol:
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Cdh8
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Gene name:
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cadherin 8
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Probe:
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Cad8 cDNA3
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Results
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Specimen
2A:
postnatal day 0
(more  )
Specimen
2A:
(close  )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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Age:
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postnatal day 0
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS27: cortical layer II |
Strong |
Regionally restricted |
2A
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A high level of expression was detected in layers 2/3 of the motor area.
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| TS27: cortical layer III |
Strong |
Regionally restricted |
2A
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A high level of expression was detected in layers 2/3 of the motor area.
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Specimen
2B:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Emx2tm1Pgr/Emx2tm1Pgr
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Age:
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postnatal day 0
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS27: cortical layer II |
Strong |
Regionally restricted |
2B
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The rostral domain of expression in the wild type cortex exhibits a caudal expansion in Emx2 mutants.
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| TS27: cortical layer III |
Strong |
Regionally restricted |
2B
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The rostral domain of expression in the wild type cortex exhibits a caudal expansion in Emx2 mutants.
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Specimen
2C:
postnatal day 0
(more )
Specimen
2C:
(close )
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Genetic Background:
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involves: C57BL/6J * DBA/2J
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Age:
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postnatal day 0
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS27: cortical layer II |
Strong |
Regionally restricted |
2C
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A high level of expression was detected in layers 2/3 of the motor area.
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| TS27: cortical layer III |
Strong |
Regionally restricted |
2C
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A high level of expression was detected in layers 2/3 of the motor area.
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Specimen
2D:
(close )
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Genetic Background:
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involves: C57BL/6J * DBA/2J
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Mutant Allele(s):
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Pax6Sey/Pax6Sey
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Age:
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postnatal day 0
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS27: cortical layer II |
Strong |
Regionally restricted |
2D
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The rostral domain of expression in the wild type cortex exhibits a rostral restriction in Pax6 mutants.
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| TS27: cortical layer III |
Strong |
Regionally restricted |
2D
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The rostral domain of expression in the wild type cortex exhibits a rostral restriction in Pax6 mutants.
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Specimen
6A:
embryonic day 18.5
(more )
Specimen
6A:
(close )
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Genetic Background:
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involves: 129X1/SvJ * C57BL/6
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: neocortex |
Present |
Regionally restricted |
6A
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Expression was restricted to rostral neocortex in layers 2/3 of the motor area.
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Specimen
6B:
(close )
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Genetic Background:
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involves: 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Emx1tm1Jlr/Emx1tm1Jlr
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: neocortex |
Present |
Regionally restricted |
6B
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Expression was unaltered in the Emx1 mutants compared with wild type.
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Analysis Tools