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Gene Expression Data
Assay Details
Assay
Reference: J:187741 Hu JK, et al., Autonomous and nonautonomous roles of Hedgehog signaling in regulating limb muscle formation. Genes Dev. 2012 Sep 15;26(18):2088-102
Assay type: RNA in situ
MGI Accession ID: MGI:6358563
Gene symbol: Six4
Gene name: sine oculis-related homeobox 4
Probe: Six4 probe2
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen S3C: embryonic day 10.5; Smotm1Amc/Smo+, Pax3tm1(cre)Joe/Pax3+ (more )
Structure Level Pattern Image Note
TS17: forelimb bud Present Regionally restricted S3C Expression was detected in forelimb muscle cells.

Specimen S3D: embryonic day 10.5; Smotm1Amc/Smotm2Amc, Pax3tm1(cre)Joe/Pax3+ (more )
Note: Conditional mutant. Pax3Cre;SmoCKO specimens can be either Pax3Cre;Smofl/fl or Pax3Cre;Smofl/del.
Structure Level Pattern Image Note
TS17: forelimb bud Present Regionally restricted S3D Expression level was not changed in the conditional knockout mutant.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory