Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Gata6tm1(EGFP/cre/ERT2)Fmw
Name:	GATA binding protein 6; targeted mutation 1, Fiona M Watt
MGI ID:	MGI:6358513
Synonyms:	Gata6EGFPCreERT2
Gene:	Gata6  Location: Chr18:11052510-11085636 bp, + strand  Genetic Position: Chr18, 5.63 cM
Alliance:	Gata6tm1(EGFP/cre/ERT2)Fmw page

Germline Transmission:	Earliest citation of germline transmission: J:246513
Parent Cell Line:	JM8 (ES Cell)
Strain of Origin:	C57BL/6N

Allele Type:    Targeted (Recombinase) Mutation:    Insertion   Gata6tm1(EGFP/cre/ERT2)Fmw expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Gata6 (MGI:107516)     A EGFPCreERT2 expression element was targeted in-frame into the first non-coding exon of the gene. (J:246513)

Activity:	Tissue activity of this recombinase allele
Driver:	Gata6 (mouse) Summary of all recombinase alleles driven by Gata6. Alliance mouse Gata6 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gata6 Mutation:	32 strains or lines available

Original:	J:246513 Donati G, et al., Wounding induces dedifferentiation of epidermal Gata6+ cells and acquisition of stem cell properties. Nat Cell Biol. 2017 Jun;19(6):603-613
All:	4 reference(s)