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Gene Expression Data
Assay Details
Assay
Reference: J:47921 Semina EV, et al., A novel homeobox gene PITX3 is mutated in families with autosomal-dominant cataracts and ASMD. Nat Genet. 1998 Jun;19(2):167-70
Assay type: RNA in situ
MGI Accession ID: MGI:6358298
Gene symbol: Pitx3
Gene name: paired-like homeodomain transcription factor 3
Probe: Pitx3 cDNA4
Probe preparation: Antisense RNA
Visualized with: Autoradiography
Results
Specimen 2a/b: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: lens Present Regionally restricted 2a/b Expressed in the bow regions.
TS24: extrinsic ocular muscle Present 2a/b

Specimen 3a/b: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: cranial muscle Present 3a/b
TS23: midbrain Present 3a/b
TS23: tongue Present 3a/b
TS23: telencephalon Present Regionally restricted 3a/b Expressed in the wall of the lateral ventricle.
TS23: upper leg mesenchyme Present Regionally restricted 3a/b Expressed in condensing mesenchyme around femur
TS23: upper leg muscle Present Regionally restricted 3a/b Expressed in condensing mesenchyme around femur

Specimen 3c/d: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: Meckel's cartilage Present 3c/d
TS22: cranial muscle Present 3c/d
TS22: extrinsic ocular muscle Present 3c/d
TS22: lens Present 3c/d
TS22: tongue Present 3c/d
TS22: head mesenchyme Present Regionally restricted 3c/d Expressed in condensing mesenchyme around hyoid bones.

Specimen 3e/h: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: midbrain Present 3e/h

Specimen 3f/i: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: incisor Present 3f/i
TS23: tongue Present 3f/i
TS23: trunk mesenchyme Present Regionally restricted 3f/i Expressed in the mesenchyme around the costal cartilage.
TS23: lip Present Regionally restricted 3f/i Expressed in lip ectoderm with adjacent mesenchyme.

Specimen 3g/j: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: upper leg mesenchyme Present Regionally restricted 3g/j Expressed in condensing mesenchyme around femur
TS23: upper leg muscle Present Regionally restricted 3g/j Expressed in condensing mesenchyme around femur

Specimen not shown: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: lens pit Present
TS16: lens placode Present

Specimen not shown: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: lens vesicle Present
TS20: midbrain Present
TS20: tongue Present
TS20: dental placode Present Regionally restricted Expressed in incisor primordia.
TS20: trunk mesenchyme Present Regionally restricted Expressed in condensing mesenchyme around the sternum and vertebrae.
TS20: skeletal musculature Present Regionally restricted Expressed in the head muscles.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory