Tg(Lepr-Bmncr)#Xhl
Transgene Detail
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| Symbol: |
Tg(Lepr-Bmncr)#Xhl |
| Name: |
transgene insertion, Xiang-Hang Luo |
| MGI ID: |
MGI:6358173 |
| Synonyms: |
Bmncr-LepRTg |
| Transgene: |
Tg(Lepr-Bmncr)#Xhl Location: unknown
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| Alliance: |
Tg(Lepr-Bmncr)#Xhl page
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Mutation details: The transgenic vector was constructed by subcloning the mouse Bmncr cDNA into a plasmid containing the Lepr promoter. The vector was then purified and microinjected into C57BL/6J F2 mouse oocytes, and the oocytes were surgically transferred into pseudopregnant C57BL/6J dams. Two lines with higher levels of Bmncr expression were selected from 6 transgenic founders and bred in C57BL/6 strain for 6 generations to obtain offspring with a defined genetic background. One line with 10-fold overexpression of Bmncr was used for studies. The pound symbol (#) is used when no line is specified and/or lines are pooled.
(J:270992)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:270992 Li CJ, et al., Long noncoding RNA Bmncr regulates mesenchymal stem cell fate during skeletal aging. J Clin Invest. 2018 Dec 3;128(12):5251-5266 |
| All: |
1 reference(s) |
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Analysis Tools
