About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:104160 Tole S, et al., Development of midline cell types and commissural axon tracts requires Fgfr1 in the cerebrum. Dev Biol. 2006 Jan 1;289(1):141-51
Assay type: RNA in situ
MGI Accession ID: MGI:6356620
Gene symbol: Otx1
Gene name: orthodenticle homeobox 1
Probe: Otx1 probe14
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen S2A control: embryonic day 15.5; Fgfr1tm1Upir/? (more )
Structure Level Pattern Image Note
TS23: cerebral cortex ventricular layer Present S2A control Expression in ventricular zone.
TS23: cortical plate Present Regionally restricted S2A control Expression in deep layers of the cortical plate.
Specimen S2A Fgfr1+/-: embryonic day 15.5; Fgfr1tm1Upir/Fgfr1+, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: cerebral cortex ventricular layer Present S2A Fgfr1+/- Authors report normal expression in heterozygous and homozygous mutants.
TS23: cortical plate Present Regionally restricted S2A Fgfr1+/- Authors report normal expression in heterozygous and homozygous mutants.
Specimen S2A Fgfr1-/-: embryonic day 15.5; Fgfr1tm1Upir/Fgfr1tm1Upir, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: cerebral cortex ventricular layer Present S2A Fgfr1-/- Authors report normal expression in heterozygous and homozygous mutants.
TS23: cortical plate Present Regionally restricted S2A Fgfr1-/- Authors report normal expression in heterozygous and homozygous mutants.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory