Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Plekhn1tm1Hkon
Name:	pleckstrin homology domain containing, family N member 1; targeted mutation 1, Hiroaki Konishi
MGI ID:	MGI:6356362
Synonyms:	CLPABP floxed
Gene:	Plekhn1  Location: Chr4:156305913-156312999 bp, - strand  Genetic Position: Chr4, 88.63 cM
Alliance:	Plekhn1tm1Hkon page

Germline Transmission:	Earliest citation of germline transmission: J:251603
Parent Cell Line:	TT2 (ES Cell)
Strain of Origin:	(C57BL/6NCrlj x CBA/JNCrlj)F1

Allele Type:    Targeted (Conditional ready) Mutation:    Insertion     Exons 3-8 were flanked with loxP sites and an frt-flanked neomycin selection cassette. (J:251603)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Plekhn1 Mutation:	55 strains or lines available

Original:	J:251603 Nishino T, et al., Antagonizing effect of CLPABP on the function of HuR as a regulator of ARE-containing leptin mRNA stability and the effect of its depletion on obesity in old male mouse. Biochim Biophys Acta. 2016 Nov;1861(11):1816-1827
All:	1 reference(s)