Gene Expression Data
Assay Details
|
Assay
|
|
Reference:
|
J:54410
Grimm C, et al., Isolation and embryonic expression of the novel mouse gene Hic1, the homologue of HIC1, a candidate gene for the Miller-Dieker syndrome. Hum Mol Genet. 1999 Apr;8(4):697-710
|
|
Assay type:
|
RNA in situ
|
|
MGI Accession ID:
|
MGI:6356044
|
|
Gene symbol:
|
Hic1
|
|
Gene name:
|
hypermethylated in cancer 1
|
|
Probe:
|
IMAGE clone 337300
|
|
Probe preparation:
|
Antisense labelled with digoxigenin RNA
|
|
Visualized with:
|
Alkaline phosphatase
|
|
|
Results
|
Specimen
6a:
embryonic day 10.5
(more  )
Note: TS17-18 embryo.
Specimen
6a:
(close  )
|
Genetic Background:
|
either: C3H/El or C57BL/6 or (involves: 102/El * C3H/El)
|
|
Age:
|
embryonic day 10.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Note:
|
TS17-18 embryo.
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS17: limb mesenchyme |
Present |
Regionally restricted |
6a
|
Expression is near the dorsal and ventral surface.
|
| TS17: head mesenchyme |
Present |
Regionally restricted |
6a
|
Expression is in cranio-facial mesenchyme near the joint anlage of the jaw and in mesenchyme connecting the trigeminal ganglion with the angle of the jaw and the eye.
|
| TS17: dermomyotome |
Present |
Regionally restricted |
6a
|
Expression is in stripes along the segmental borders of the sclerotomes and and dermomyotomes spreading along the rostro-caudal direction.
|
| TS17: sclerotome |
Present |
Regionally restricted |
6a
|
Expression is in stripes along the segmental borders of the sclerotomes and and dermomyotomes spreading along the rostro-caudal direction.
|
| TS17: nasal mesenchyme |
Present |
|
6a
|
|
Specimen
6b:
embryonic day 11.5
(more )
Specimen
6b:
(close )
|
Genetic Background:
|
either: C3H/El or C57BL/6 or (involves: 102/El * C3H/El)
|
|
Age:
|
embryonic day 11.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
Specimen
6d:
embryonic day 11.5
(more )
Specimen
6d:
(close )
|
Genetic Background:
|
either: C3H/El or C57BL/6 or (involves: 102/El * C3H/El)
|
|
Age:
|
embryonic day 11.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS19: myotome |
Present |
|
6d
|
|
| TS19: paraxial mesenchyme |
Present |
Regionally restricted |
6d
|
Expression is in the lateral body wall.
|
| TS19: trunk mesenchyme |
Present |
Regionally restricted |
6d
|
Expression is in mesenchyme between and dorsal to the spinal ganglia where the dorsal roots enter the spinal cord.
|
Specimen
6d':
embryonic day 11.5
(more )
Specimen
6d':
(close )
|
Genetic Background:
|
either: C3H/El or C57BL/6 or (involves: 102/El * C3H/El)
|
|
Age:
|
embryonic day 11.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section from whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS19: dermomyotome |
Present |
Regionally restricted |
6d'
|
Expression is in epaxial and hypaxial mesenchyme.
|
Specimen
6e:
embryonic day 10.75
(more )
Note: TS17-18 embryo.
Specimen
6e:
(close )
|
Genetic Background:
|
either: C3H/El or C57BL/6 or (involves: 102/El * C3H/El)
|
|
Age:
|
embryonic day 10.75
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Note:
|
TS17-18 embryo.
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS18: dermomyotome |
Present |
Regionally restricted |
6e
|
Expression is in epaxial and hypaxial mesenchyme.
|
| TS18: trunk mesenchyme |
Present |
Regionally restricted |
6e
|
Expression is in mesenchyme overlying the dermomyotomes spreading in a rostro-caudal direction.
|
| TS18: limb mesenchyme |
Present |
Regionally restricted |
6e
|
Expression is near the dorsal and ventral surface.
|
Specimen
6e':
embryonic day 10.75
(more )
Note: TS17-18 embryo.
Specimen
6e':
(close )
|
Genetic Background:
|
either: C3H/El or C57BL/6 or (involves: 102/El * C3H/El)
|
|
Age:
|
embryonic day 10.75
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Note:
|
TS17-18 embryo.
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS18: dermomyotome |
Present |
Regionally restricted |
6e'
|
Expression is in epaxial and hypaxial mesenchyme.
|
| TS18: trunk mesenchyme |
Present |
Regionally restricted |
6e'
|
Expression is medial and lateral surrounding the epaxial and hypaxial demomyotome derivatives.
|
Specimen
6f:
embryonic day 11.5
(more )
Specimen
6f:
(close )
|
Genetic Background:
|
either: C3H/El or C57BL/6 or (involves: 102/El * C3H/El)
|
|
Age:
|
embryonic day 11.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS19: trunk mesenchyme |
Present |
Regionally restricted |
6f
|
Expression is in mesenchyme between and dorsal to the spinal ganglia where the dorsal roots enter the spinal cord and outlines the vertebral arches and ribs.
|
| TS19: limb mesenchyme |
Present |
|
6f
|
|
Specimen
6g:
embryonic day 10.75
(more )
Note: TS17-18 embryo.
Specimen
6g:
(close )
|
Genetic Background:
|
either: C3H/El or C57BL/6 or (involves: 102/El * C3H/El)
|
|
Age:
|
embryonic day 10.75
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Note:
|
TS17-18 embryo.
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS18: dermomyotome |
Present |
Regionally restricted |
6g
|
Expression is in epaxial and hypaxial mesenchyme.
|
| TS18: limb mesenchyme |
Present |
Regionally restricted |
6g
|
Expression is near the dorsal and ventral surface.
|
Specimen
6h:
embryonic day 12.5
(more )
Specimen
6h:
(close )
|
Genetic Background:
|
either: C3H/El or C57BL/6 or (involves: 102/El * C3H/El)
|
|
Age:
|
embryonic day 12.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS20: trunk mesenchyme |
Present |
Regionally restricted |
6h
|
Expression is in mesenchyme between and dorsal to the spinal ganglia where the dorsal roots enter the spinal cord and in continuous bands at the levels of epaxial and hypaxial somite derivatives, and outlines the vertebral arches and ribs.
|
| TS20: limb mesenchyme |
Present |
|
6h
|
|
| TS20: gut |
Present |
Regionally restricted |
6h
|
|
| TS20: metanephros |
Present |
Regionally restricted |
6h
|
|
| TS20: pancreas |
Present |
Regionally restricted |
6h
|
|
| TS20: urogenital ridge |
Present |
Regionally restricted |
6h
|
|
| TS20: endocrine gland |
Present |
Regionally restricted |
6h
|
Expression is in the adrenal gland.
|
Specimen
7a:
embryonic day 11.5
(more )
Specimen
7a:
(close )
|
Genetic Background:
|
either: C3H/El or C57BL/6 or (involves: 102/El * C3H/El)
|
|
Age:
|
embryonic day 11.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
Specimen
7b:
embryonic day 11.5
(more )
Specimen
7b:
(close )
|
Genetic Background:
|
either: C3H/El or C57BL/6 or (involves: 102/El * C3H/El)
|
|
Age:
|
embryonic day 11.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
Specimen
7c:
embryonic day 14.5
(more )
Specimen
7c:
(close )
|
Genetic Background:
|
either: C3H/El or C57BL/6 or (involves: 102/El * C3H/El)
|
|
Age:
|
embryonic day 14.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS22: trunk mesenchyme |
Present |
Regionally restricted |
7c
|
Expression is in mesenchyme surrounding peripheral nerves.
|
Specimen
7d:
embryonic day 14.5
(more )
Specimen
7d:
(close )
|
Genetic Background:
|
either: C3H/El or C57BL/6 or (involves: 102/El * C3H/El)
|
|
Age:
|
embryonic day 14.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS22: trunk mesenchyme |
Present |
Regionally restricted |
7d
|
Expression is in epaxial and hypaxial mesenchyme associated with muscles and in mesenchyme surrounding peripheral nerves.
|
Specimen
7e:
embryonic day 11.5
(more )
Specimen
7e:
(close )
|
Genetic Background:
|
either: C3H/El or C57BL/6 or (involves: 102/El * C3H/El)
|
|
Age:
|
embryonic day 11.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS19: limb mesenchyme |
Present |
Regionally restricted |
7e
|
Expression is in mesenchyme outlining the precartilagenous condensations and surrounding peripheral nerves.
|
Specimen
7f:
embryonic day 15.5
(more )
Specimen
7f:
(close )
|
Genetic Background:
|
either: C3H/El or C57BL/6 or (involves: 102/El * C3H/El)
|
|
Age:
|
embryonic day 15.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
Specimen
7f':
embryonic day 14.5
(more )
Specimen
7f':
(close )
|
Genetic Background:
|
either: C3H/El or C57BL/6 or (involves: 102/El * C3H/El)
|
|
Age:
|
embryonic day 14.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS22: limb mesenchyme |
Present |
Regionally restricted |
7f'
|
Expression is in mesenchyme outlining the precartilagenous condensations.
|
Specimen
7g:
embryonic day 13.5
(more )
Specimen
7g:
(close )
|
Genetic Background:
|
either: C3H/El or C57BL/6 or (involves: 102/El * C3H/El)
|
|
Age:
|
embryonic day 13.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS21: limb |
Strong |
Regionally restricted |
7g
|
Expression is along the caudal and rostral edges.
|
Specimen
7h:
embryonic day 12.5
(more )
Specimen
7h:
(close )
|
Genetic Background:
|
either: C3H/El or C57BL/6 or (involves: 102/El * C3H/El)
|
|
Age:
|
embryonic day 12.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS20: trunk mesenchyme |
Present |
Regionally restricted |
7h
|
Expression is in epaxial and hypaxial mesenchyme associated with muscles and in mesenchyme surrounding epaxial and hypaxial peripheral nerves and is absent surrounding the proximal branches of the nerves.
|
| TS20: limb mesenchyme |
Present |
Regionally restricted |
7h
|
Expression is in mesenchyme outlining the precartilagenous condensations and surrounding peripheral nerves.
|
Specimen
8a:
embryonic day 11.5
(more )
Specimen
8a:
(close )
|
Genetic Background:
|
either: C3H/El or C57BL/6 or (involves: 102/El * C3H/El)
|
|
Age:
|
embryonic day 11.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS19: head mesenchyme |
Present |
Regionally restricted |
8a
|
Expression is in cranio-facial mesenchyme near the joint anlage of the jaw, around the cranial nerves, and in mesenchyme connecting the trigeminal ganglion with the angle of the jaw and the eye.
|
| TS19: nasal mesenchyme |
Present |
|
8a
|
|
| TS19: branchial arch mesenchyme |
Present |
Regionally restricted |
8a
|
Expression is in the caudal arches.
|
Specimen
8c:
embryonic day 11.5
(more )
Specimen
8c:
(close )
|
Genetic Background:
|
either: C3H/El or C57BL/6 or (involves: 102/El * C3H/El)
|
|
Age:
|
embryonic day 11.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
Specimen
8d:
embryonic day 11.5
(more )
Specimen
8d:
(close )
|
Genetic Background:
|
either: C3H/El or C57BL/6 or (involves: 102/El * C3H/El)
|
|
Age:
|
embryonic day 11.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS19: head mesenchyme |
Present |
Regionally restricted |
8d
|
Expression is in mesenchyme connecting the trigeminal ganglion with the angle of the jaw and the eye and around the cranial nerves.
|
| TS19: branchial arch mesenchyme |
Present |
Regionally restricted |
8d
|
Expression is in the caudal arches.
|
| TS19: lens vesicle |
Absent |
|
8d
|
|
Specimen
8e:
embryonic day 14.5
(more )
Specimen
8e:
(close )
|
Genetic Background:
|
either: C3H/El or C57BL/6 or (involves: 102/El * C3H/El)
|
|
Age:
|
embryonic day 14.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
Specimen
8f:
embryonic day 14.5
(more )
Specimen
8f:
(close )
|
Genetic Background:
|
either: C3H/El or C57BL/6 or (involves: 102/El * C3H/El)
|
|
Age:
|
embryonic day 14.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
Specimen
8g:
embryonic day 14.5
(more )
Specimen
8g:
(close )
|
Genetic Background:
|
either: C3H/El or C57BL/6 or (involves: 102/El * C3H/El)
|
|
Age:
|
embryonic day 14.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
Specimen
8h:
embryonic day 14.5
(more )
Specimen
8h:
(close )
|
Genetic Background:
|
either: C3H/El or C57BL/6 or (involves: 102/El * C3H/El)
|
|
Age:
|
embryonic day 14.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
Specimen
not shown, TS12:
embryonic day 8.0
(more )
Specimen
not shown, TS12:
(close )
|
Genetic Background:
|
either: C3H/El or C57BL/6 or (involves: 102/El * C3H/El)
|
|
Age:
|
embryonic day 8.0
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
Specimen
not shown, TS13:
embryonic day 8.5
(more )
Specimen
not shown, TS13:
(close )
|
Genetic Background:
|
either: C3H/El or C57BL/6 or (involves: 102/El * C3H/El)
|
|
Age:
|
embryonic day 8.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
Specimen
not shown, TS14:
embryonic day 9.0
(more )
Specimen
not shown, TS14:
(close )
|
Genetic Background:
|
either: C3H/El or C57BL/6 or (involves: 102/El * C3H/El)
|
|
Age:
|
embryonic day 9.0
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
Specimen
not shown, TS15:
embryonic day 9.5
(more )
Specimen
not shown, TS15:
(close )
|
Genetic Background:
|
either: C3H/El or C57BL/6 or (involves: 102/El * C3H/El)
|
|
Age:
|
embryonic day 9.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS15: dermomyotome |
Present |
Regionally restricted |
|
Expression is in stripes along the segmental borders of the sclerotomes and and dermomyotomes in the occipitocervical region.
|
| TS15: sclerotome |
Present |
Regionally restricted |
|
Expression is in stripes along the segmental borders of the sclerotomes and and dermomyotomes in the occipitocervical region.
|
Specimen
not shown, p1:
postnatal day 1
(more )
Specimen
not shown, p1:
(close )
|
Genetic Background:
|
either: C3H/El or (involves: 102/El * C3H/El)
|
|
Age:
|
postnatal day 1
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS27: lens |
Absent |
|
|
|
Specimen
not shown, p7:
postnatal day 7
(more )
Specimen
not shown, p7:
(close )
|
Genetic Background:
|
either: C3H/El or (involves: 102/El * C3H/El)
|
|
Age:
|
postnatal day 7
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: lens |
Absent |
|
|
|
Specimen
not shown, p14:
postnatal day 14
(more )
Specimen
not shown, p14:
(close )
|
Genetic Background:
|
either: C3H/El or (involves: 102/El * C3H/El)
|
|
Age:
|
postnatal day 14
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: lens |
Absent |
|
|
|
Specimen
not shown, p21:
postnatal day 21
(more )
Specimen
not shown, p21:
(close )
|
Genetic Background:
|
either: C3H/El or (involves: 102/El * C3H/El)
|
|
Age:
|
postnatal day 21
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: lens |
Absent |
|
|
|
Specimen
not shown, adult:
postnatal adult
(more )
Specimen
not shown, adult:
(close )
|
Genetic Background:
|
either: C3H/El or (involves: 102/El * C3H/El)
|
|
Age:
|
postnatal adult
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: lens |
Absent |
|
|
|
|
Analysis Tools