Tg(Nppa-luc,Nppb-Katshuka)1Vmc
Transgene Detail
|
Symbol: |
Tg(Nppa-luc,Nppb-Katshuka)1Vmc |
Name: |
transgene insertion 1, Vincent M Christoffels |
MGI ID: |
MGI:6356007 |
Synonyms: |
AC336-Katushka-Luciferas, BAC336LK |
Transgene: |
Tg(Nppa-luc,Nppb-Katshuka)1Vmc Location: unknown
|
Alliance: |
Tg(Nppa-luc,Nppb-Katshuka)1Vmc page
|
|
|
Transgene Type: |
|
Transgenic (Reporter) |
Mutation: |
|
Insertion
|
|
|
Mutation details: The BAC336 clone of a mouse 129 SvJ BAC library was modified to create the transgene construct. This clone contains both the Nppa and Nppb genes. The sequences cccacgccagcATGggc and cggcATGgatc at the translation start sites of Nppa and Nppb were replaced by firefly Luciferase and dimeric bright red fluorescent protein Katushka, respectively. Two mouse lines were generated with randomly integrated multiple copies of the Luciferase-Katushka BAC construct (BAC336LK, lines 1 and 2.
(J:229075, J:275070)
|
|
|
|
Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
|
Original: |
J:229075 Sergeeva IA, et al., A transgenic mouse model for the simultaneous monitoring of ANF and BNP gene activity during heart development and disease. Cardiovasc Res. 2014 Jan 1;101(1):78-86 |
All: |
8 reference(s) |
|