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Ormdl3tm1.1Dhbe
Targeted Allele Detail
Summary
Symbol: Ormdl3tm1.1Dhbe
Name: ORM1-like 3 (S. cerevisiae); targeted mutation 1.1, David H Broide
MGI ID: MGI:6343506
Synonyms: Ormdl3loxP
Gene: Ormdl3  Location: Chr11:98472120-98478071 bp, - strand  Genetic Position: Chr11, 62.07 cM
Alliance: Ormdl3tm1.1Dhbe page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:247806
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion
 
Mutation detailsAn frt-flanked neomycin selectin cassette was inserted upsteream of exon 2 and a second loxP site was inserted downstream of exon 3. The neomycin selection cassette was removed via FLP-mediated recombination. (J:247806)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ormdl3 Mutation:  10 strains or lines available
References
Original:  J:247806 Miller M, et al., Cutting Edge: Targeting Epithelial ORMDL3 Increases, Rather than Reduces, Airway Responsiveness and Is Associated with Increased Sphingosine-1-Phosphate. J Immunol. 2017 Apr 15;198(8):3017-3022
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory