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Gene Expression Data
Assay Details
Assay
Reference: J:74069 Morris-Wiman J, et al., Temporospatial distribution of matrix metalloproteinase and tissue inhibitors of matrix metalloproteinases during murine secondary palate morphogenesis. Anat Embryol (Berl). 2000 Aug;202(2):129-41
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6342632
Gene symbol: Timp3
Gene name: tissue inhibitor of metalloproteinase 3
Antibody: anti-Timp-3
Detection system: fluorescein
Assay notes: Fixation with acid alcohol.
Results
Specimen 3G: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: palatal shelf epithelium Present Regionally restricted 3G Enhanced expression within nasal and oral areas.
TS20: dental placode Present 3G Expression within presumptive tooth germ.
TS20: palatal shelf mesenchyme Trace 3G Minimal expresion within mesenchymal areas.
Specimen 3H: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: palatal shelf epithelium Strong Regionally restricted 3H Enhanced expression within nasal and oral palatal epithelium.
TS21: tooth epithelium Present 3H Expression within tooth germ epithelium.
TS21: tooth mesenchyme Strong Regionally restricted 3H Increased expression associated with tooth germ mesenchyme.
TS21: palatal shelf mesenchyme Present Regionally restricted 3H Some expression within mid-oral mesenchyme and ventral medial mesenchyme.
Specimen 3I: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: palatal shelf epithelium Present 3I Expression maintained within palatal epithelium.
TS22: tooth mesenchyme Present 3I Expression in tooth germ mesenchyme.
TS22: palatal shelf mesenchyme Weak Regionally restricted 3I Slight expression within medial mesenchyme surrounding regressing palatal seam, ventral medial and mid-oral mesenchyme.
Specimen gd 14-fused not shown: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: palatal shelf mesenchyme Absent
TS22: tooth mesenchyme Present Expression remained within tooth germ mesenchyme.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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01/06/2026
MGI 6.24 		The Jackson Laboratory