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Gene Expression Data
Assay Details
Assay
Reference: J:28212 Iseki S, et al., Localization of transforming growth factor-beta type I and type II receptors in mouse development. Exp Cell Res. 1995 Aug;219(2):339-47
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6342481
Gene symbol: Tgfbr2
Gene name: transforming growth factor, beta receptor II
Results
Specimen 1D: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS19: Meckel's cartilage pre-cartilage condensation Present 1D Specific expression localized in undifferentiated mesenchyme which differentiates into Meckel's cartilage.
Specimen 1B: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: Meckel's cartilage Strong 1B
TS21: lower jaw mesenchyme Present Regionally restricted 1B Specific expression localized in undifferentiated mesenchyme which differentiates into Meckel's cartilage.
Specimen 1E: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: Meckel's cartilage Present 1E
TS22: tooth epithelium Present 1E
Specimen 1F: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: Meckel's cartilage Weak 1F
Specimen 2B: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: chondrocranium Strong Regionally restricted 2B Strong expression in undifferentiated mesenchyme and in cartilage which subsequently ossifies endochondrally.
Specimen 2C: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: maxilla Strong 2C
TS21: palatal shelf mesenchyme Strong 2C
Specimen 2D: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: maxilla Strong 2D
TS22: palatal shelf mesenchyme Strong 2D
TS22: upper jaw mesenchyme Present Regionally restricted 2D Expression in mesenchyme surrounding tooth bud.
Specimen 4B: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: lower jaw tooth epithelium Strong Regionally restricted 4B Intense expression in morphogenetically active epithelium of tooth bud.
TS21: lower jaw mesenchyme Present Regionally restricted 4B Expression in loose mesenchyme surrounding condensed mesenchyme of tooth bud.
Specimen 4D: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: submandibular gland primordium epithelium Present Regionally restricted 4D Expression localized in invaginating and branching epithelium
Specimen 4F: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: lung epithelium Present Regionally restricted 4F Expression in pulmonary epithelium which is cuboidal in morphology. No expression in columnar epithelium.
Specimen 4H: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: lip Present Regionally restricted 4H Expression in invaginating epithelium of lip furrow band.
Specimen E12 not shown: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: chondrocranium Weak Regionally restricted Weaker expression in undifferentiated mesenchyme below which forms base of skull by endochondral ossification.
Specimen E16 not shown: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: Meckel's cartilage Absent
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory