Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Pirttm3.1(cre)Xzd
Name:	phosphoinositide-interacting regulator of transient receptor potential channels; targeted mutation 3.1, Xinzhong Dong
MGI ID:	MGI:6332952
Synonyms:	Pirt-cre
Gene:	Pirt  Location: Chr11:66802807-66820702 bp, + strand  Genetic Position: Chr11, 40.59 cM
Alliance:	Pirttm3.1(cre)Xzd page

Germline Transmission:	Earliest citation of germline transmission: J:101977
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129

Allele Type:    Targeted (Null/knockout, Recombinase) Mutation:    Insertion   Pirttm3.1(cre)Xzd expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Pirt (MGI:2443635)   Mutation details: Cre expression cassette replaced the entire ORF of the Pirt gene to be under the control of Pirt regulation. The neo-selection cassette was removed. (J:101977)

Activity:	Tissue activity of this recombinase allele
Driver:	Pirt (mouse) Summary of all recombinase alleles driven by Pirt. Alliance mouse Pirt gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pirt Mutation:	13 strains or lines available

Original:	J:247573 Kim YS, et al., Coupled Activation of Primary Sensory Neurons Contributes to Chronic Pain. Neuron. 2016 Sep 07;91(5):1085-1096
All:	18 reference(s)