Summary | Transgene origin | Transgene description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tg(Atoh1-flpo/ERT2)#Alj
Name:	transgene insertion, Alexandra L Joyner
MGI ID:	MGI:6331265
Synonyms:	Atoh-FlpoER
Transgene:	Tg(Atoh1-flpo/ERT2)#Alj  Location: unknown
Alliance:	Tg(Atoh1-flpo/ERT2)#Alj page

Strain of Origin:

Not Specified

Transgene Type:    Transgenic (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Tg(Atoh1-flpo/ERT2)#Alj expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note mouse Atoh1 (MGI:104654)   Mutation details: The transgene was designed with a 1.4 kb mouse Atoh1 3' enhancer (and a beta-globin minimal promoter) sequence upstream of an Flp sequence optimized for translation in mammalian cells (Flpo) joined to the ERT2 mutated estrogen receptor ligand-binding domain by the linker sequence from the Flpe/ERT2 cassette. Founder information and line numbers were not available. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:272495)

Activity:	Tissue activity of this recombinase allele
Driver:	Atoh1 (mouse) Summary of all recombinase alleles driven by Atoh1. Alliance mouse Atoh1 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:272495 Wojcinski A, et al., Genetic deletion of genes in the cerebellar rhombic lip lineage can stimulate compensation through adaptive reprogramming of ventricular zone-derived progenitors. Neural Dev. 2019 Feb 14;14(1):4
All:	2 reference(s)