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Gene Expression Data
Assay Details
Assay
Reference: J:229536 Kawasaki K, et al., Expression of Sox genes in tooth development. Int J Dev Biol. 2015;59(10-12):471-8
Assay type: RNA in situ
MGI Accession ID: MGI:6331228
Gene symbol: Sox4
Gene name: SRY (sex determining region Y)-box 4
Probe: Sox4 probe3
Probe preparation: Antisense labelled with S35 RNA
Results
Specimen 2A: embryonic day 10.5 (more )
Note: Initiation stage of tooth development.
Structure Level Pattern Image Note
TS17: 1st branchial arch ectoderm Present Regionally restricted 2A Expression is in the presumptive tooth epithelium.
TS17: oral region epithelium Present Regionally restricted 2A Expression is in the presumptive tooth epithelium.
TS17: 1st branchial arch mesenchyme Present Regionally restricted 2A Expression is in the presumptive tooth mesenchyme.
Specimen 2B: embryonic day 11.5 (more )
Note: Initiation stage of tooth development.
Structure Level Pattern Image Note
TS19: dental placode Present Regionally restricted 2B Expression is in the presumptive tooth epithelium and mesenchyme.
Specimen 2C: embryonic day 13.5 (more )
Note: Bud stage of tooth development.
Structure Level Pattern Image Note
TS21: tooth mesenchyme Strong 2C
TS21: tooth epithelium Strong Regionally restricted 2C Expression is at the center.
Specimen 2D: embryonic day 14.5 (more )
Note: Cap stage of tooth development.
Structure Level Pattern Image Note
TS22: inner enamel epithelium Present 2D
TS22: stellate reticulum Present 2D
TS22: dental papilla Present 2D
TS22: tooth mesenchyme Present Regionally restricted 2D Expression is in the mesenchyme facing buccal outer enamel epithelium.
TS22: outer enamel epithelium Weak 2D
Specimen 2E: embryonic day 18.5 (more )
Note: Cytodifferentiation stage of tooth development.
Structure Level Pattern Image Note
TS26: tooth Absent 2E
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory