Tg(Ctsl-Gdnf/EGFP)1Reb
Transgene Detail
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| Symbol: |
Tg(Ctsl-Gdnf/EGFP)1Reb |
| Name: |
transgene insertion 1, Robert E Braun |
| MGI ID: |
MGI:6331132 |
| Synonyms: |
Tg(Gdnf) |
| Transgene: |
Tg(Ctsl-Gdnf/EGFP)1Reb Location: unknown
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| Alliance: |
Tg(Ctsl-Gdnf/EGFP)1Reb page
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| Transgene Type: |
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Transgenic (Inserted expressed sequence, Reporter) |
| Mutation: |
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Insertion
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Tg(Ctsl-Gdnf/EGFP)1Reb expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Note |
| mouse |
Gdnf (MGI:107430) |
mouse promoter and cDNA |
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Mutation details: A mouse Gdnf cDNA was cloned in-frame with the EGFP from the Pem212 clone, where human MT2A intron 1 was inserted into the EGFP coding region at nucleotide 898. The Pem promoter was then replaced by the Cathepsin L KpnI-SalI promoter/intron 1 fragment from a luciferase reporter construct. One of six characterized transgenic lines was used for further analysis.
(J:260462)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:260462 Sharma M, et al., Cyclical expression of GDNF is required for spermatogonial stem cell homeostasis. Development. 2018 Mar 1;145(5):dev151555 |
| All: |
3 reference(s) |
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Analysis Tools
