Clec4ftm2.1(icre)Ciphe
Targeted Allele Detail
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Symbol: |
Clec4ftm2.1(icre)Ciphe |
Name: |
C-type lectin domain family 4, member f; targeted mutation 2.1, Centre d'ImmunoPhenomique |
MGI ID: |
MGI:6330738 |
Synonyms: |
B6-Clec4fm2Ciphe, Clec4f-cre, Clec4f-IRES-iCRE, Clec4ftm1.1(icre)Ciphe |
Gene: |
Clec4f Location: Chr6:83621524-83633098 bp, - strand Genetic Position: Chr6, 35.94 cM
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Alliance: |
Clec4ftm2.1(icre)Ciphe page
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Germline Transmission: |
Earliest citation of germline transmission:
J:274437
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Parent Cell Line: |
JM8.F6 (ES Cell)
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Strain of Origin: |
C57BL/6N
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Allele Type: |
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Targeted (Recombinase) |
Mutation: |
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Insertion
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Clec4ftm2.1(icre)Ciphe expression driven by
1 gene
Knock-in expression driven by:
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Mutation details: An IRES-iCRE-loxP-Cre-NeoR-loxP cassette was introduced in the 3' untranslated region of the Clec4f
gene, downstream of the stop codon by homologous recombination. Germline transmission led to the self-excision of the loxP-Cre-NeoR-loxP cassette in male germinal cells.
(J:274437)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Clec4f
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Clec4f Mutation: |
28 strains or lines available
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Original: |
J:274437 Scott CL, et al., The Transcription Factor ZEB2 Is Required to Maintain the Tissue-Specific Identities of Macrophages. Immunity. 2018 Aug 21;49(2):312-325.e5 |
All: |
5 reference(s) |
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