Summary | Transgene origin | Transgene description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tg(Slc6a4-cre)#Ito
Name:	transgene insertion, Shigeyoshi Itohara
MGI ID:	MGI:6324519
Synonyms:	5-HTTCre Tg, Tg(Slc6a4-cre)#Rerz
Transgene:	Tg(Slc6a4-cre)#Ito  Location: unknown
Alliance:	Tg(Slc6a4-cre)#Ito page

Strain of Origin:

C57BL/6

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(Slc6a4-cre)#Ito expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note mouse Slc6a4 (MGI:96285)   Mutation details: Tg construct was created by modifying the RP23-39F11 mouse BAC clone to insert the nuclear localization signal (NLS) Cre-pA cassette and FRT-Amp-FRT sequence into the translational initiation site of the Slc6a4 gene. The Amp sequence in the obtained BAC construct was removed by flp/FRT recombination in bacteria. The Tg founder mice were generated by microinjection of linearized constructs into C57BL/6 fertilized eggs. At least six lines were generated and two lines (208 and 810) were identified with similar expression patterns. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:216132)

Activity:	Tissue activity of this recombinase allele
Driver:	Slc6a4 (mouse) Summary of all recombinase alleles driven by Slc6a4. Comparative matrix view of recombinase activities Alliance mouse Slc6a4 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:216132 Arakawa H, et al., Thalamic NMDA receptor function is necessary for patterning of the thalamocortical somatosensory map and for sensorimotor behaviors. J Neurosci. 2014 Sep 3;34(36):12001-14
All:	2 reference(s)