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Gene Expression Data
Assay Details
Assay
Reference: J:29971 Meyer D, et al., Multiple essential functions of neuregulin in development [see comments] [published erratum appears in Nature 1995 Dec 14;378(6558):753]. Nature. 1995 Nov 23;378(6555):386-90
Assay type: RNA in situ
MGI Accession ID: MGI:6315893
Gene symbol: Erbb3
Gene name: erb-b2 receptor tyrosine kinase 3
Probe: erbB3 probe2
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 3a: embryonic day 10.5; Nrg1tm1Cbm/Nrg1+ (more )
Structure Level Pattern Image Note
TS17: cranial ganglion Present 3a
TS17: dorsal root ganglion Present 3a
TS17: otocyst Present 3a
Specimen 3b: embryonic day 10.5; Nrg1tm1Cbm/Nrg1+ (more )
Structure Level Pattern Image Note
TS17: cranial ganglion Present 3b
TS17: otocyst Present 3b
Specimen 3c: embryonic day 10.5; Nrg1tm1Cbm/Nrg1+ (more )
Structure Level Pattern Image Note
TS17: dorsal root ganglion Present 3c Expression includes their axonal projections
TS17: spinal nerve Present 3c Expression includes their axonal projections
Specimen 3d: embryonic day 10.5; Nrg1tm1Cbm/Nrg1tm1Cbm (more )
Structure Level Pattern Image Note
TS17: cranial ganglion Present 3d Expression is reduced in this mutant.
TS17: dorsal root ganglion Present 3d
TS17: otocyst Present 3d
Specimen 3e: embryonic day 10.5; Nrg1tm1Cbm/Nrg1tm1Cbm (more )
Structure Level Pattern Image Note
TS17: cranial ganglion Present 3e Expression is reduced in this mutant.
TS17: otocyst Present 3e
Specimen 3f: embryonic day 10.5; Nrg1tm1Cbm/Nrg1tm1Cbm (more )
Structure Level Pattern Image Note
TS17: dorsal root ganglion Present 3f
Specimen 3g: embryonic day 10.5; Nrg1tm1Cbm/Nrg1+ (more )
Structure Level Pattern Image Note
TS17: dorsal root ganglion Present 3g
TS17: myotome Present 3g
TS17: spinal nerve Present Regionally restricted 3g Expression is in Schwann cell precursors located along axonal projections of motor or sensory nerves.
Specimen 3h: embryonic day 10.5; Nrg1tm1Cbm/Nrg1+ (more )
Structure Level Pattern Image Note
TS17: spinal nerve Present 3h Expression is in Schwann cell precursors located along axonal projections of motor or sensory nerves.
Specimen 3i: embryonic day 10.5; Nrg1tm1Cbm/Nrg1tm1Cbm (more )
Structure Level Pattern Image Note
TS17: spinal nerve Weak 3i Expression is in a reduced number of Schwann cell precursors located along axonal projections of motor or sensory nerves.
Specimen 3k: embryonic day 9.25; Nrg1tm1Cbm/Nrg1tm1Cbm (more )
Structure Level Pattern Image Note
TS15: migrating neural crest Present Regionally restricted 3k Expression is in neural crest cells emanating from the hindbrain and in trunk neural crest.
TS15: central nervous system Absent 3k
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory