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Tg(tetO-SOX9)1Xy
Transgene Detail
Summary
Symbol: Tg(tetO-SOX9)1Xy
Name: transgene insertion 1, Xin Yuan
MGI ID: MGI:6315862
Transgene: Tg(tetO-SOX9)1Xy  Location: unknown  Genetic Position: ChrX, Syntenic
Alliance: Tg(tetO-SOX9)1Xy page
Transgene
origin
Strain of Origin:  FVB/NCrl
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inducible, Inserted expressed sequence)
Inducer:    doxycycline/tetracycline
Mutation:    Insertion
 
Tg(tetO-SOX9)1Xy expresses 1 gene
 
Mutation detailsThe 1.8kb transgenic construct contains a FLAG-tagged human Sox9 cDNA and an SV40 polyadenylation signal driven by the tetracycline operator (tetO). The transgene inserted on the X chromosome. (J:196713)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:196713 Wang H, et al., SOX9 regulates low density lipoprotein receptor-related protein 6 (LRP6) and T-cell factor 4 (TCF4) expression and Wnt/beta-catenin activation in breast cancer. J Biol Chem. 2013 Mar 1;288(9):6478-87
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory