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Gene Expression Data
Assay Details
Assay
Reference: J:123725 Lax S, et al., CD248/Endosialin is dynamically expressed on a subset of stromal cells during lymphoid tissue development, splenic remodeling and repair. FEBS Lett. 2007 Jul 24;581(18):3550-6
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6314775
Gene symbol: Cd248
Gene name: CD248 antigen, endosialin
Antibody: P13
Detection system: Secondary antibody
Results
Specimen 1A E16: embryonic day 16.0 (more )
Note: Double labeled: green - Cd248; gray - Cd3e (assay MGI:6314777).
Structure Level Pattern Image Note
TS24: spleen Strong Regionally restricted 1A E16 Expression is mostly in the red pulp.
Specimen 1A Day 2: postnatal day 2 (more )
Note: Double labeled: green - Cd248; gray - Cd3e (assay MGI:6314777).
Structure Level Pattern Image Note
TS27: spleen Present 1A Day 2
Specimen 1A 2 week: postnatal week 2 (more )
Note: Double labeled: green - Cd248; gray - Cd3e (assay MGI:6314777).
Structure Level Pattern Image Note
TS28: spleen Present 1A 2 week
Specimen 1A 6 week: postnatal week 6 (more )
Note: Double labeled: green - Cd248; gray - Cd3e (assay MGI:6314777).
Structure Level Pattern Image Note
TS28: spleen Present Regionally restricted 1A 6 week Expression is predominantly on vascular-like cells.
TS28: spleen red pulp Weak Regionally restricted 1A 6 week Expression is on interstitial fibroblasts.
Specimen 1B E16: embryonic day 16.0 (more )
Note: Double labeled: green - Cd248; gray - Cd3e (assay MGI:6314777).
Structure Level Pattern Image Note
TS24: thymus Strong Regionally restricted 1B E16 Expression is in developing vascular-like structures within the epithelial medulla and the outer layer of mesenchymal cells.
Specimen 1B Day 2: postnatal day 2 (more )
Note: Double labeled: green - Cd248; gray - Cd3e (assay MGI:6314777).
Structure Level Pattern Image Note
TS27: thymus Present 1B Day 2
Specimen 1B 2 week: postnatal week 2 (more )
Note: Double labeled: green - Cd248; gray - Cd3e (assay MGI:6314777).
Structure Level Pattern Image Note
TS28: thymus Present 1B 2 week
Specimen 1B 6 week: postnatal week 5 (more )
Note: Double labeled: green - Cd248; gray - Cd3e (assay MGI:6314777).
Structure Level Pattern Image Note
TS28: thymus Weak 1B 6 week
Specimen 1C E16: embryonic day 16.0 (more )
Note: Double labeled: green - Cd248; gray - Cd3e (assay MGI:6314777).
Structure Level Pattern Image Note
TS24: hemolymphoid system Strong Regionally restricted 1C E16 Expression is mostly confined to the outer mesenchymal layers of cells of the lymph node.
Specimen 1C Day 2: postnatal day 2 (more )
Note: Double labeled: green - Cd248; gray - Cd3e (assay MGI:6314777).
Structure Level Pattern Image Note
TS27: lymph node Strong Widespread 1C Day 2
Specimen 1C 2 week: postnatal week 2 (more )
Note: Double labeled: green - Cd248; gray - Cd3e (assay MGI:6314777).
Structure Level Pattern Image Note
TS28: lymph node Present 1C 2 week
Specimen 1C 6 week: postnatal week 6 (more )
Note: Double labeled: green - Cd248; gray - Cd3e (assay MGI:6314777).
Structure Level Pattern Image Note
TS28: lymph node Present Regionally restricted 1C 6 week Expression is restricted to vascular like structures.
TS28: lymph node follicle Weak Regionally restricted 1C 6 week Expression is in fibroblasts in the interstitial follicular area.
Specimen 2A E16: embryonic day 16.0 (more )
Note: Double labeled: green - Cd248; red - Pecam1 (assay MGI:6314779).
Structure Level Pattern Image Note
TS24: spleen Present 2A E16
Specimen 2A Day 2: postnatal day 2 (more )
Note: Double labeled: green - Cd248; red - Pecam1 (assay MGI:6314779).
Structure Level Pattern Image Note
TS27: spleen Present 2A Day 2
Specimen 2A 2 week: postnatal week 2 (more )
Note: Double labeled: green - Cd248; red - Pecam1 (assay MGI:6314779).
Structure Level Pattern Image Note
TS28: spleen Present 2A 2 week
Specimen 2A 6 week: postnatal week 6 (more )
Note: Double labeled: green - Cd248; red - Pecam1 (assay MGI:6314779).
Structure Level Pattern Image Note
TS28: spleen Present 2A 6 week
Specimen 2B E16: embryonic day 16.0 (more )
Note: Double labeled: green - Cd248; red - Pecam1 (assay MGI:6314779).
Structure Level Pattern Image Note
TS24: thymus Present 2B E16
Specimen 2B Day 2: postnatal day 2 (more )
Note: Double labeled: green - Cd248; red - Pecam1 (assay MGI:6314779).
Structure Level Pattern Image Note
TS27: thymus Present 2B Day 2
Specimen 2B 2 week: postnatal week 2 (more )
Note: Double labeled: green - Cd248; red - Pecam1 (assay MGI:6314779).
Structure Level Pattern Image Note
TS28: thymus Present 2B 2 week
Specimen 2B 6 week: postnatal week 6 (more )
Note: Double labeled: green - Cd248; red - Pecam1 (assay MGI:6314779).
Structure Level Pattern Image Note
TS28: thymus Present 2B 6 week
Specimen 2C E16: embryonic day 16.0 (more )
Note: Double labeled: green - Cd248; red - Pecam1 (assay MGI:6314779).
Structure Level Pattern Image Note
TS24: hemolymphoid system Present 2C E16
Specimen 2C Day 2: postnatal day 2 (more )
Note: Double labeled: green - Cd248; red - Pecam1 (assay MGI:6314779).
Structure Level Pattern Image Note
TS27: lymph node Present 2C Day 2
Specimen 2C 2 week: postnatal week 2 (more )
Note: Double labeled: green - Cd248; red - Pecam1 (assay MGI:6314779).
Structure Level Pattern Image Note
TS28: lymph node Present 2C 2 week
Specimen 2C 6 week: postnatal week 6 (more )
Note: Double labeled: green - Cd248; red - Pecam1 (assay MGI:6314779).
Structure Level Pattern Image Note
TS28: lymph node Present 2C 6 week
Specimen 3A E16: embryonic day 16.0 (more )
Note: Triple labeled: green - Cd248; red - Vcam1 (assay MGI:6314780); blue - ER-TR7 (reticular fibroblast marker).
Structure Level Pattern Image Note
TS24: spleen Present Regionally restricted 3A E16 Expression is in stromal cells.
Specimen 3A Day 2: postnatal day 2 (more )
Note: Triple labeled: green - Cd248; red - Vcam1 (assay MGI:6314780); blue - ER-TR7 (reticular fibroblast marker).
Structure Level Pattern Image Note
TS27: spleen Present Regionally restricted 3A Day 2
Specimen 3A 2 week: postnatal week 2 (more )
Note: Triple labeled: green - Cd248; red - Vcam1 (assay MGI:6314780); blue - ER-TR7 (reticular fibroblast marker).
Structure Level Pattern Image Note
TS28: spleen Present Regionally restricted 3A 2 week
Specimen 3A 6 week: postnatal week 6 (more )
Note: Triple labeled: green - Cd248; red - Vcam1 (assay MGI:6314780); blue - ER-TR7 (reticular fibroblast marker).
Structure Level Pattern Image Note
TS28: spleen Present Regionally restricted 3A 6 week
Specimen 3B E16: embryonic day 16.0 (more )
Note: Triple labeled: green - Cd248; red - Vcam1 (assay MGI:6314780); blue - ER-TR7 (reticular fibroblast marker).
Structure Level Pattern Image Note
TS24: thymus Present Regionally restricted 3B E16 Expression is in the epithelial medulla and surrounding mesenchyme.
Specimen 3B Day 2: postnatal day 2 (more )
Note: Triple labeled: green - Cd248; red - Vcam1 (assay MGI:6314780); blue - ER-TR7 (reticular fibroblast marker).
Structure Level Pattern Image Note
TS27: thymus Present 3B Day 2
Specimen 3B 2 week: postnatal week 2 (more )
Note: Triple labeled: green - Cd248; red - Vcam1 (assay MGI:6314780); blue - ER-TR7 (reticular fibroblast marker).
Structure Level Pattern Image Note
TS28: thymus Present 3B 2 week
Specimen 3B 6 week: postnatal week 6 (more )
Note: Triple labeled: green - Cd248; red - Vcam1 (assay MGI:6314780); blue - ER-TR7 (reticular fibroblast marker).
Structure Level Pattern Image Note
TS28: thymus Present 3B 6 week
Specimen 3C E16: embryonic day 16.0 (more )
Note: Triple labeled: green - Cd248; red - Vcam1 (assay MGI:6314780); blue - ER-TR7 (reticular fibroblast marker).
Structure Level Pattern Image Note
TS24: hemolymphoid system Present Regionally restricted 3C E16 Expression is in the inner medulla of the lymph node.
Specimen 3C Day 2: postnatal day 2 (more )
Note: Triple labeled: green - Cd248; red - Vcam1 (assay MGI:6314780); blue - ER-TR7 (reticular fibroblast marker).
Structure Level Pattern Image Note
TS27: lymph node Present 3C Day 2
Specimen 3C 2 week: postnatal week 2 (more )
Note: Triple labeled: green - Cd248; red - Vcam1 (assay MGI:6314780); blue - ER-TR7 (reticular fibroblast marker).
Structure Level Pattern Image Note
TS28: lymph node Present 3C 2 week
Specimen 3C 6 week: postnatal week 6 (more )
Note: Triple labeled: green - Cd248; red - Vcam1 (assay MGI:6314780); blue - ER-TR7 (reticular fibroblast marker).
Structure Level Pattern Image Note
TS28: lymph node medulla Present Regionally restricted 3C 6 week Expression is vascular.
TS28: lymph node B cell domain Present Regionally restricted 3C 6 week Expression is in a small single positive population within the B cell follicular zone.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory