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Gene Expression Data
Assay Details
Assay
Reference: J:275336 Sulistomo HW, et al., Formin homology 2 domain-containing 3 (Fhod3) controls neural plate morphogenesis in mouse cranial neurulation by regulating multidirectional apical constriction. J Biol Chem. 2019 Feb 22;294(8):2924-2934
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6314399
Gene symbol: Ctnna1
Gene name: catenin alpha 1
Antibody: alpha18
Detection system: Alexa Fluor 488
Assay notes: Fixation was with 3.7% paraformaldehyde.
Results
Specimen 5B +/+ alpha18 upper: embryonic day 9.5 (more )
Note: Double labeled: green - alpha18 (Ctnna1); red - MHC IIB (Myh10 assay MGI:6314397).
Structure Level Pattern Image Note
TS15: rhombomere 4 lateral wall Present Regionally restricted 5B +/+ upper alpha18 , 5B +/+ upper merge Expression at apical surface of lateral plate.
Specimen 5B +/+ alpha18 lower: embryonic day 9.5 (more )
Note: Double labeled: green - alpha18 (Ctnna1); red - MHC IIB (Myh10 assay MGI:6314397).
Structure Level Pattern Image Note
TS15: rhombomere 4 lateral wall Present Regionally restricted 5B +/+ lower merge , 5B +/+ lower alpha18 Expression at apical surface of lateral plate.
Specimen 5B -/- alpha18 upper: embryonic day 9.5; Fhod3tm1Hsum/Fhod3tm1Hsum (more )
Note: Double labeled: green - alpha18 (Ctnna1); red - MHC IIB (Myh10 assay MGI:6314397).
Structure Level Pattern Image Note
TS15: rhombomere 4 lateral wall Weak Regionally restricted 5B -/- upper alpha18 , 5B -/- upper merge Authors report expression at apical surface was attenuated.
Specimen 5B -/- alpha18 lower: embryonic day 9.5; Fhod3tm1Hsum/Fhod3tm1Hsum (more )
Note: Double labeled: green - alpha18 (Ctnna1); red - MHC IIB (Myh10 assay MGI:6314397).
Structure Level Pattern Image Note
TS15: rhombomere 4 lateral wall Weak Regionally restricted 5B -/- lower alpha18 , 5B -/- lower merge Authors report expression at apical surface was attenuated.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
MGI 6.23 		The Jackson Laboratory