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Gene Expression Data
Assay Details
Assay
Reference: J:41386 Vielkind U, et al., Changing patterns of cell adhesion molecules during mouse pelage hair follicle development. 2. Follicle morphogenesis in the hair mutants, Tabby and downy. Acta Anat (Basel). 1996;157(3):183-94
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6307794
Gene symbol: Cdh1
Gene name: cadherin 1
Antibody: clone ECCD-2 (#13-1900)
Detection system: Secondary antibody coupled to fluorescein
Results
Specimen 1B: embryonic day 14.0; EdaTa-J/? (more )
Note: the mutation is X-linked; the embryo could have been homozygous or hemizygous
Structure Level Pattern Image Note
TS22: epidermis Present Regionally restricted 1B Expression was detected in the cuboidal cells of the basal epidermal layer.
TS22: periderm Present 1B

Specimen not shown: embryonic day 15.0; EdaTa-J/? (more )
Note: the mutation is X-linked; the embryo could have been homozygous or hemizygous
Structure Level Pattern Image Note
TS23: epidermis Strong Regionally restricted Intense staining was detected in the upper epidermal layer.
TS23: periderm Strong

Specimen 2A: embryonic day 16.0; EdaTa-J/? (more )
Note: the mutation is X-linked; the embryo could have been homozygous or hemizygous
Structure Level Pattern Image Note
TS24: epidermis Strong 2A As in wild type, staining was intense in the epidermis.
TS24: hair epidermal placode Ambiguous 2A
TS24: hair follicle Ambiguous 2A

Specimen 2E: embryonic day 16.0; EdaTa-J/? (more )
Note: the mutation is X-linked; the embryo could have been homozygous or hemizygous
Structure Level Pattern Image Note
TS24: epidermis Strong 2E As in wild type, staining was intense in the epidermis.
TS24: hair epidermal placode Ambiguous 2E
TS24: hair follicle Ambiguous 2E

Specimen 3C: embryonic day 17.0; EdaTa-J/? (more )
Note: the mutation is X-linked; the embryo could have been homozygous or hemizygous
Structure Level Pattern Image Note
TS25: hair bulb Weak Regionally restricted 3C Faint staining was detected in the future hair matrix. The staining pattern of awl hair plugs was virtually identical to wild type.

Specimen 4A: embryonic day 18.0; EdaTa-J/? (more )
Note: the mutation is X-linked; the embryo could have been homozygous or hemizygous
Structure Level Pattern Image Note
TS26: hair bulb Absent 4A Absent staining from the future hair matrix.

Specimen 5B: embryonic day 15.0; dny/dny (more )
Structure Level Pattern Image Note
TS23: epidermis Present Regionally restricted 5B In most skin areas, the basal epidermal layer was of normal thickness and stained less intensely than the rest of the epidermis. In some areas, however, the basal epidermal layer was thinner and was stained intensely.

Specimen 6B: embryonic day 17.0; dny/dny (more )
Structure Level Pattern Image Note
TS25: epidermis Strong Regionally restricted 6B In some areas the basal epidermal layer was intensely stained.

Specimen 6F: embryonic day 17.0; dny/dny (more )
Structure Level Pattern Image Note
TS25: epidermis Present 6F

Specimen 7C: embryonic day 19.0; dny/dny (more )
Structure Level Pattern Image Note
TS26: hair follicle Present 7C Normal staining pattern was noted in the morphologically abnormal follicles.
TS26: hair bulb Absent 7C
TS26: hair inner root sheath Absent 7C


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/30/2025
MGI 6.24
The Jackson Laboratory