About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:222159 Li Y, et al., Global genetic analysis in mice unveils central role for cilia in congenital heart disease. Nature. 2015 May 28;521(7553):520-4
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6307095
Gene symbol: Ift88
Gene name: intraflagellar transport 88
Results
Specimen 1o: embryonic day 12.5 (more )
Note: Double labeled: green - Ift88; red - acetylated tubulin.
Structure Level Pattern Image Note
TS20: atrioventricular endocardial cushion Present 1o
Specimen 1p: embryonic day 12.5; Cc2d2ab2b1035Clo/Cc2d2ab2b1035Clo (more )
Note: Double labeled: green - Ift88; red - acetylated tubulin.
Structure Level Pattern Image Note
TS20: atrioventricular endocardial cushion Ambiguous Regionally restricted 1p Authors report no cilia in atrioventricular cushion.
Specimen 1q: embryonic day 12.5 (more )
Note: Double labeled: green - Ift88; red - acetylated tubulin.
Structure Level Pattern Image Note
TS20: outflow tract endocardial cushion Present 1q
Specimen 1r: embryonic day 12.5; Cc2d2ab2b1035Clo/Cc2d2ab2b1035Clo (more )
Note: Double labeled: green - Ift88; red - acetylated tubulin.
Structure Level Pattern Image Note
TS20: outflow tract endocardial cushion Present Regionally restricted 1r Authors report normal ciliation in outflow tract cushion.
Specimen 1s: embryonic day 12.5 (more )
Note: Double labeled: green - Ift88; red - acetylated tubulin.
Structure Level Pattern Image Note
TS20: brain ventricular layer Present 1s
Specimen 1t: embryonic day 12.5; Cc2d2ab2b1035Clo/Cc2d2ab2b1035Clo (more )
Note: Double labeled: green - Ift88; red - acetylated tubulin.
Structure Level Pattern Image Note
TS20: brain ventricular layer Weak Regionally restricted 1t Authors report fewer and shorter cilia in other mutant tissues.
Specimen 1u: embryonic day 12.5 (more )
Note: Double labeled: green - Ift88; red - acetylated tubulin.
Structure Level Pattern Image Note
TS20: mandibular process mesenchyme Present 1u
Specimen 1v: embryonic day 12.5; Cc2d2ab2b1035Clo/Cc2d2ab2b1035Clo (more )
Note: Double labeled: green - Ift88; red - acetylated tubulin.
Structure Level Pattern Image Note
TS20: mandibular process mesenchyme Weak Regionally restricted 1v Authors report fewer and shorter cilia in other mutant tissues.
Specimen 1w: embryonic day 12.5 (more )
Note: Double labeled: green - Ift88; red - acetylated tubulin.
Structure Level Pattern Image Note
TS20: limb mesenchyme Present 1w
Specimen 1x: embryonic day 12.5; Cc2d2ab2b1035Clo/Cc2d2ab2b1035Clo (more )
Note: Double labeled: green - Ift88; red - acetylated tubulin.
Structure Level Pattern Image Note
TS20: limb mesenchyme Weak Regionally restricted 1x Authors report fewer and shorter cilia in other mutant tissues.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory