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Gene Expression Data
Assay Details
Assay
Reference: J:190657 Cho JH, et al., Slits and Robo-2 regulate the coalescence of subsets of olfactory sensory neuron axons within the ventral region of the olfactory bulb. Dev Biol. 2012 Nov 15;371(2):269-79
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6306737
Gene symbol: Or4e5
Gene name: olfactory receptor family 4 subfamily E member 5
Results
Specimen 1J: postnatal day 0; Or4e5tm4Rax/Or4e5+ (more )
Note: Double labeled: green - Olfr1507; red - Robo2 (assay MGI:6306738).
Structure Level Pattern Image Note
TS27: main olfactory bulb Present Regionally restricted 1K'' , 1J , 1K' Expression was detected in axons in the ventral region of the olfactory bulb.
Specimen 6A: postnatal month 3; Or4e5tm4Rax/Or4e5+ (more )
Note: Control genotype could have included Robo2+/lox, or Omp-cre.
Structure Level Pattern Image Note
TS28: main olfactory bulb Present Regionally restricted 6A A beta-galactosidase positive glomerulus was observed in the lateral region of the olfactory bulb.
Specimen 6B: postnatal month 3; Or4e5tm4Rax/Or4e5+, Omptm1(cre)Jae/Omp+, Robo2tm1Rilm/Robo2tm1Rilm (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: main olfactory bulb Present Regionally restricted 6B A beta-galactosidase positive glomerulus was observed in the lateral region of the olfactory bulb.
Specimen 6C: postnatal month 3; Or4e5tm4Rax/Or4e5+ (more )
Note: Control genotype could have included Robo2+/lox, or Omp-cre.
Structure Level Pattern Image Note
TS28: main olfactory bulb Present Regionally restricted 6C A second beta-galactosidase positive glomerulus was observed more caudally on the lateral side of the olfactory bulb in 19/29 controls.
Specimen 6D: postnatal month 3; Or4e5tm4Rax/Or4e5+, Omptm1(cre)Jae/Omp+, Robo2tm1Rilm/Robo2tm1Rilm (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: main olfactory bulb Present Regionally restricted 6D A second beta-galactosidase positive glomerulus was observed more caudally on the lateral side of the olfactory bulb in 13/19 mutants.
Specimen 6F: postnatal month 3; Or4e5tm4Rax/Or4e5+ (more )
Note: Control genotype could have included Robo2+/lox, or Omp-cre.
Structure Level Pattern Image Note
TS28: main olfactory bulb Present Regionally restricted 6F At least one beta-galactosidase positive glomerulus was observed in the medial region of the olfactory bulb. There were two in 20/26 controls.
Specimen 6G: postnatal month 3; Or4e5tm4Rax/Or4e5+, Omptm1(cre)Jae/Omp+, Robo2tm1Rilm/Robo2tm1Rilm (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: main olfactory bulb Present Regionally restricted 6G At least one beta-galactosidase positive glomerulus was observed in the medial region of the olfactory bulb.
Specimen 6H: postnatal month 3; Or4e5tm4Rax/Or4e5+, Omptm1(cre)Jae/Omp+, Robo2tm1Rilm/Robo2tm1Rilm (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: main olfactory bulb Present Regionally restricted 6H At least one beta-galactosidase positive glomerulus was observed in the medial region of the olfactory bulb.
Specimen 7A: postnatal month 3; Or4e5tm4Rax/Or4e5+ (more )
Note: Control genotype could have included Slit1+/-.
Structure Level Pattern Image Note
TS28: main olfactory bulb Present Regionally restricted 7A A beta-galactosidase positive glomerulus was observed in the lateral region of the olfactory bulb.
Specimen 7B: postnatal month 3; Or4e5tm4Rax/Or4e5+, Slit1tm1.1Matl/Slit1tm1.1Matl (more )
Structure Level Pattern Image Note
TS28: main olfactory bulb Present Regionally restricted 7B A beta-galactosidase positive glomerulus was observed in the lateral region of the olfactory bulb.
Specimen 7C: postnatal month 3; Or4e5tm4Rax/Or4e5+ (more )
Note: Control genotype could have included Slit1+/-.
Structure Level Pattern Image Note
TS28: main olfactory bulb Present Regionally restricted 7C A second beta-galactosidase positive glomerulus was observed more caudally on the lateral side of the olfactory bulb in 19/29 controls.
Specimen 7D: postnatal month 3; Or4e5tm4Rax/Or4e5+, Slit1tm1.1Matl/Slit1tm1.1Matl (more )
Structure Level Pattern Image Note
TS28: main olfactory bulb Present Regionally restricted 7D A second beta-galactosidase positive glomerulus was observed more caudally on the lateral side of the olfactory bulb in 11/22 mutants.
Specimen 7F: postnatal month 3; Or4e5tm4Rax/Or4e5+ (more )
Note: Control genotype could have included Slit1+/-.
Structure Level Pattern Image Note
TS28: main olfactory bulb Present Regionally restricted 7F At least one beta-galactosidase positive glomerulus was observed in the medial region of the olfactory bulb. There were two in 20/26 controls.
Specimen 7G: postnatal month 3; Or4e5tm4Rax/Or4e5+, Slit1tm1.1Matl/Slit1tm1.1Matl (more )
Structure Level Pattern Image Note
TS28: main olfactory bulb Present Regionally restricted 7G At least one beta-galactosidase positive glomerulus was observed in the medial region of the olfactory bulb. There were two in 17/24 mutants.
Specimen 7H: postnatal month 3; Or4e5tm4Rax/Or4e5+ (more )
Note: Control genotype could have included Slit1+/-.
Structure Level Pattern Image Note
TS28: main olfactory bulb Present Regionally restricted 7H A beta-galactosidase positive glomerulus was observed in the ventromedial region of the olfactory bulb.
Specimen 7I: postnatal month 3; Or4e5tm4Rax/Or4e5+, Slit1tm1.1Matl/Slit1tm1.1Matl (more )
Structure Level Pattern Image Note
TS28: main olfactory bulb Present Regionally restricted 7I A beta-galactosidase positive glomerulus was observed in the ventromedial region of the olfactory bulb. There was a small but significant dorsal shift in the location of the glomerulus in the mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory