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Gene Expression Data
Assay Details
Assay
Reference: J:190657 Cho JH, et al., Slits and Robo-2 regulate the coalescence of subsets of olfactory sensory neuron axons within the ventral region of the olfactory bulb. Dev Biol. 2012 Nov 15;371(2):269-79
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6306733
Gene symbol: Or10a4
Gene name: olfactory receptor family 10 subfamily A member 4
Results
Specimen 1H: postnatal day 0; Or10a4tm1Mom/Or10a4+ (more )
Note: Double labeled: red - Olfr17; green - Robo2 (assay MGI:6306738).
Structure Level Pattern Image Note
TS27: main olfactory bulb Present Regionally restricted 1I'' , 1H , 1I' Expression was detected in axons in the ventral region of the olfactory bulb.
Specimen 4A: postnatal month 3; Or10a4tm1Mom/Or10a4+ (more )
Note: Double labeled: red - Olfr17; green - Nqo1 (assay MGI:6306889). Control genotype could have included Robo2+/lox, or Omp-cre.
Structure Level Pattern Image Note
TS28: main olfactory bulb Present Regionally restricted 4A A beta-galactosidase positive glomerulus was observed on the lateral side of the olfactory bulb.
Specimen 4B: postnatal month 3; Or10a4tm1Mom/Or10a4+, Omptm1(cre)Jae/Omp+, Robo2tm1Rilm/Robo2tm1Rilm (more )
Note: Conditional mutant. Double labeled: red - Olfr17; green - Nqo1 (assay MGI:6306889).
Structure Level Pattern Image Note
TS28: main olfactory bulb Present Regionally restricted 4B A beta-galactosidase positive glomerulus was observed on the lateral side of the olfactory bulb.
Specimen 4C: postnatal month 3; Or10a4tm1Mom/Or10a4+ (more )
Note: Double labeled: red - Olfr17; green - Nqo1 (assay MGI:6306889). Control genotype could have included Robo2+/lox, or Omp-cre.
Structure Level Pattern Image Note
TS28: main olfactory bulb Present Regionally restricted 4C A second beta-galactosidase positive glomerulus was observed on the lateral side of the olfactory bulb in 20/35 controls.
Specimen 4D: postnatal month 3; Or10a4tm1Mom/Or10a4+, Omptm1(cre)Jae/Omp+, Robo2tm1Rilm/Robo2tm1Rilm (more )
Note: Conditional mutant. Double labeled: red - Olfr17; green - Nqo1 (assay MGI:6306889).
Structure Level Pattern Image Note
TS28: main olfactory bulb Present Regionally restricted 4D A second beta-galactosidase positive glomerulus was observed on the lateral side of the olfactory bulb in 17/20 conditional mutants.
Specimen 4E: postnatal month 3; Or10a4tm1Mom/Or10a4+, Omptm1(cre)Jae/Omp+, Robo2tm1Rilm/Robo2tm1Rilm (more )
Note: Conditional mutant. Double labeled: red - Olfr17; green - Nqo1 (assay MGI:6306889).
Structure Level Pattern Image Note
TS28: main olfactory bulb Present Regionally restricted 4E Additional beta-galactosidase positive glomeruli were observed more ventrally in the olfactory bulb in 8/20 conditional mutants.
Specimen 4F: postnatal month 3; Or10a4tm1Mom/Or10a4+ (more )
Note: Double labeled: red - Olfr17; green - Nqo1 (assay MGI:6306889). Discrepancy: This pane was labeled as a conditional mutant. However, the figure legend refers to it as a control. Control genotype could have included Robo2+/lox, or Omp-cre.
Structure Level Pattern Image Note
TS28: main olfactory bulb Present Regionally restricted 4F Beta-galactosidase positive glomeruli were observed on the medial side of the olfactory bulb.
Specimen 4G: postnatal month 3; Or10a4tm1Mom/Or10a4+, Omptm1(cre)Jae/Omp+, Robo2tm1Rilm/Robo2tm1Rilm (more )
Note: Conditional mutant. Double labeled: red - Olfr17; green - Nqo1 (assay MGI:6306889).
Structure Level Pattern Image Note
TS28: main olfactory bulb Present Regionally restricted 4G Beta-galactosidase positive glomeruli were observed on the medial side of the olfactory bulb. There was an overall ventral shift in the location of the glomeruli in the conditional mutant compared to controls.
Specimen 5A: postnatal month 3; Or10a4tm1Mom/Or10a4+ (more )
Note: Double labeled: red - Olfr17; green - Nqo1 (assay MGI:6306889). Control genotype could have included Slit1+/-.
Structure Level Pattern Image Note
TS28: main olfactory bulb Present Regionally restricted 5A A beta-galactosidase positive glomerulus was observed on the lateral side of the olfactory bulb.
Specimen 5B: postnatal month 3; Or10a4tm1Mom/Or10a4+, Slit1tm1.1Matl/Slit1tm1.1Matl (more )
Note: Double labeled: red - Olfr17; green - Nqo1 (assay MGI:6306889).
Structure Level Pattern Image Note
TS28: main olfactory bulb Present Regionally restricted 5B A beta-galactosidase positive glomerulus was observed on the lateral side of the olfactory bulb.
Specimen 5C: postnatal month 3; Or10a4tm1Mom/Or10a4+ (more )
Note: Double labeled: red - Olfr17; green - Nqo1 (assay MGI:6306889). Control genotype could have included Slit1+/-.
Structure Level Pattern Image Note
TS28: main olfactory bulb Present Regionally restricted 5C A second beta-galactosidase positive glomerulus was observed more caudally on the lateral side of the olfactory bulb in 21/38 controls.
Specimen 5D: postnatal month 3; Or10a4tm1Mom/Or10a4+, Slit1tm1.1Matl/Slit1tm1.1Matl (more )
Note: Double labeled: red - Olfr17; green - Nqo1 (assay MGI:6306889).
Structure Level Pattern Image Note
TS28: main olfactory bulb Present Regionally restricted 5D A second beta-galactosidase positive glomerulus was observed more caudally on the lateral side of the olfactory bulb in 17/24 mutants. The position of the glomerulus was shifted ventrally in the mutant.
Specimen 5F: postnatal month 3; Or10a4tm1Mom/Or10a4+ (more )
Note: Double labeled: red - Olfr17; green - Nqo1 (assay MGI:6306889). Control genotype could have included Slit1+/-.
Structure Level Pattern Image Note
TS28: main olfactory bulb Present Regionally restricted 5F A beta-galactosidase positive glomerulus was observed on the medial side of the olfactory bulb. In 21/38 controls there were two.
Specimen 5G: postnatal month 3; Or10a4tm1Mom/Or10a4+, Slit1tm1.1Matl/Slit1tm1.1Matl (more )
Note: Double labeled: red - Olfr17; green - Nqo1 (assay MGI:6306889).
Structure Level Pattern Image Note
TS28: main olfactory bulb Present Regionally restricted 5G A beta-galactosidase positive glomerulus was observed on the medial side of the olfactory bulb. There were two in 21/26 mutants. The position of the glomerulus was shifted ventrally in the mutant.
Specimen 5H: postnatal month 3; Or10a4tm1Mom/Or10a4+ (more )
Note: Double labeled: red - Olfr17; green - Nqo1 (assay MGI:6306889). Control genotype could have included Slit1+/-.
Structure Level Pattern Image Note
TS28: main olfactory bulb Present Regionally restricted 5H A beta-galactosidase positive glomerulus was observed on the medial side of the olfactory bulb.
Specimen 5I: postnatal month 3; Or10a4tm1Mom/Or10a4+, Slit1tm1.1Matl/Slit1tm1.1Matl (more )
Note: Double labeled: red - Olfr17; green - Nqo1 (assay MGI:6306889).
Structure Level Pattern Image Note
TS28: main olfactory bulb Present Regionally restricted 5I A beta-galactosidase positive glomerulus was observed on the medial side of the olfactory bulb. The position of the glomerulus was shifted ventrally in the mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/30/2024
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