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Gene Expression Data
Assay Details
Assay
Reference: J:186799 Nieminen P, et al., Inactivation of IL11 signaling causes craniosynostosis, delayed tooth eruption, and supernumerary teeth. Am J Hum Genet. 2011 Jul 15;89(1):67-81
Assay type: RNA in situ
MGI Accession ID: MGI:6306499
Gene symbol: Il11ra1
Gene name: interleukin 11 receptor subunit alpha 1
Probe: Il11ra cDNA7
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 5A: embryonic day 17.0 (more )
Structure Level Pattern Image Note
TS25: molar dental papilla Strong 5A
Specimen 5B: embryonic day 17.0 (more )
Structure Level Pattern Image Note
TS25: head mesenchyme Strong Regionally restricted 5B Expressed in the calvarial mesenchyme of the (prospective) sagittal suture.
TS25: cranium Absent 5B
Specimen 5D: embryonic day 17.0 (more )
Structure Level Pattern Image Note
TS25: molar dental papilla Strong 5D
Specimen 5E: postnatal day 4 (more )
Structure Level Pattern Image Note
TS28: head Strong Regionally restricted 5E Expressed in calvarial mesenchyme.
TS28: frontal suture Strong 5E
TS28: chondrocranium bone Absent 5E
Specimen 5G: postnatal day 4 (more )
Structure Level Pattern Image Note
TS28: molar dental pulp Strong Regionally restricted 5G The expression was weaker in the coronal region of the pulp and absent from the odontoblasts.
TS28: molar crown Absent 5G No expression in the ameloblasts.
Specimen 5H: postnatal day 4 (more )
Structure Level Pattern Image Note
TS28: hard palate Strong Regionally restricted 5H Expressed in the mesenchyme of the secondary palate including the palatal suture. No expression in the differentiated osteoblasts and bone matrix deposition.
Specimen not shown: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: head mesenchyme Present Uniform Expressed in craniofacial mesenchymal tissues.
Specimen not shown: embryonic day 17.0 (more )
Structure Level Pattern Image Note
TS25: incisor dental papilla Strong
TS25: mandible Absent
TS25: maxilla Absent
TS25: lower jaw mesenchyme Strong Regionally restricted Expressed in the osteogenic mesenchyme surrounding the forming bones.
TS25: upper jaw mesenchyme Strong Regionally restricted Expressed in the osteogenic mesenchyme surrounding the forming bones.
Specimen not shown: postnatal day 4 (more )
Structure Level Pattern Image Note
TS28: frontonasal suture Strong
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory