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Gene Expression Data
Assay Details
Assay
Reference: J:218850 Bisson JA, et al., Wnt5a and Wnt11 inhibit the canonical Wnt pathway and promote cardiac progenitor development via the Caspase-dependent degradation of AKT. Dev Biol. 2015 Feb 1;398(1):80-96
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6305282
Gene symbol: Isl1
Gene name: ISL1 transcription factor, LIM/homeodomain
Antibody: Anti-ISL-1 Antibody (AB4326)
Detection system: Secondary antibody coupled to DyLight 594
Results
Specimen S1A/C: embryonic day 9.5 (more )
Note: Triple labeled: red - Isl1; green - Plxna2 (assay MGI:6305283); blue - Hoechst.
Structure Level Pattern Image Note
TS15: outflow tract Present Regionally restricted S1C , S1A Co-expression with Plxna2 in cells within posterior wall of outflow tract. Expression within anterior wall of outflow tract in cells no expression Plxna2.
Specimen S1D/F: embryonic day 9.5; Wnt11tm1Amc/Wnt11tm1Amc, Wnt5atm1Amc/Wnt5atm1Amc (more )
Note: Triple labeled: red - Isl1; green - Plxna2 (assay MGI:6305283); blue - Hoechst.
Structure Level Pattern Image Note
TS15: outflow tract Weak Regionally restricted S1F , S1D Reduced or absent expression in both anterior and posterior walls of outflow tract as well as ouflow tract lumen. Expression maintained in roof of outflow tract.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory