Gene Expression Data
Assay Details
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Assay
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Reference:
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J:244196
Roux I, et al., Assessment of the expression and role of the alpha1-nAChR subunit in efferent cholinergic function during the development of the mammalian cochlea. J Neurophysiol. 2016 Aug 01;116(2):479-92
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Assay type:
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In situ reporter (knock in)
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MGI Accession ID:
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MGI:6305147
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Gene symbol:
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Chrna1
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Gene name:
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cholinergic receptor nicotinic alpha 1 subunit
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Reporter:
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lacZ
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Direct Detection
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Assay notes:
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Data was quantified in Fig. 2E.
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Results
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Specimen
2A:
(close  )
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Genetic Background:
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involves: C57BL/6
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Mutant Allele(s):
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Chrna1tm1b(EUCOMM)Hmgu/Chrna1+
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Age:
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postnatal day 8
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: organ of Corti |
Present |
Widespread |
2A
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Expressed all along the cochlea.
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Specimen
2B E17:
(close )
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Genetic Background:
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involves: C57BL/6
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Mutant Allele(s):
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Chrna1tm1b(EUCOMM)Hmgu/Chrna1+
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Age:
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embryonic day 17.0
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Specimen
2B P4:
(close )
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Genetic Background:
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involves: C57BL/6
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Mutant Allele(s):
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Chrna1tm1b(EUCOMM)Hmgu/Chrna1+
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Age:
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postnatal day 4
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: organ of Corti |
Present |
Regionally restricted |
2B P4
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Expressed in the inner hair cell region.
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Specimen
2B P8:
(close )
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Genetic Background:
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involves: C57BL/6
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Mutant Allele(s):
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Chrna1tm1b(EUCOMM)Hmgu/Chrna1+
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Age:
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postnatal day 8
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: organ of Corti |
Present |
Regionally restricted |
2B P8
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Expressed in the inner and outer hair cell regions.
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Specimen
2B P16:
(close )
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Genetic Background:
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involves: C57BL/6
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Mutant Allele(s):
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Chrna1tm1b(EUCOMM)Hmgu/Chrna1+
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Age:
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postnatal day 16
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: organ of Corti |
Present |
Regionally restricted |
2B P16
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Expressed in the inner hair cell region.
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Specimen
2B 6 weeks:
(close )
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Genetic Background:
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involves: C57BL/6
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Mutant Allele(s):
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Chrna1tm1b(EUCOMM)Hmgu/Chrna1+
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Age:
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postnatal week 6
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: organ of Corti |
Present |
Regionally restricted |
2B 6 weeks
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Expressed in the inner hair cell region.
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Specimen
2B 6 months:
(close )
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Genetic Background:
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involves: C57BL/6
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Mutant Allele(s):
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Chrna1tm1b(EUCOMM)Hmgu/Chrna1+
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Age:
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postnatal month 6
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: organ of Corti |
Present |
Regionally restricted |
2B 6 months
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Expressed in the inner hair cell region.
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Specimen
2B 18 months:
(close )
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Genetic Background:
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involves: C57BL/6
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Mutant Allele(s):
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Chrna1tm1b(EUCOMM)Hmgu/Chrna1+
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Age:
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postnatal month 18
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: organ of Corti |
Present |
Regionally restricted |
2B 18 months
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Expressed in the inner hair cell region.
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Specimen
not shown:
(close )
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Genetic Background:
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involves: C57BL/6
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Mutant Allele(s):
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Chrna1tm1b(EUCOMM)Hmgu/Chrna1+
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Age:
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postnatal
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Specimen
not shown:
(close )
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Genetic Background:
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involves: C57BL/6
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Mutant Allele(s):
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Chrna1tm1b(EUCOMM)Hmgu/Chrna1+
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Age:
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embryonic day 17.0
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Analysis Tools
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