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Gene Expression Data
Assay Details
Assay
Reference: J:188806 Hurd EA, et al., Delayed fusion and altered gene expression contribute to semicircular canal defects in Chd7 deficient mice. Mech Dev. 2012 Sep;129(9-12):308-23
Assay type: RNA in situ
MGI Accession ID: MGI:6305140
Gene symbol: Otx1
Gene name: orthodenticle homeobox 1
Probe: Otx1 probe13
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 4A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: otocyst Present Regionally restricted 4A Expression was detected in the lateral compartment of the otocyst.
Specimen 4B: embryonic day 10.5; Chd7Gt(S20-7E1)Sor/Chd7+ (more )
Structure Level Pattern Image Note
TS17: otocyst Present Regionally restricted 4B Expression was detected in the lateral compartment of the otocyst.
Specimen 4C: embryonic day 10.5; Chd7Gt(S20-7E1)Sor/Chd7Gt(S20-7E1)Sor (more )
Structure Level Pattern Image Note
TS17: otocyst Absent 4C
Specimen 4D: embryonic day 10.5; Chd7tm1.1Dmm/Chd7+, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: otocyst Present Regionally restricted 4D Expression was detected in the lateral compartment of the otocyst, as in wild type.
Specimen 4E: embryonic day 10.5; Chd7Gt(S20-7E1)Sor/Chd7tm1.1Dmm, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: otocyst Present Regionally restricted 4E Expression was reduced in the lateral compartment of the otocyst.
Specimen 5I: embryonic day 11.5; Chd7tm1.1Dmm/Chd7+ (more )
Structure Level Pattern Image Note
TS19: inner ear Present Regionally restricted 5I Expression was in dorsolateral inner ear.
Specimen 5J: embryonic day 11.5; Chd7tm1.1Dmm/Chd7+, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: inner ear Present Regionally restricted 5J Expression was in dorsolateral inner ear.
Specimen 5K: embryonic day 11.5; Chd7Gt(S20-7E1)Sor/Chd7tm1.1Dmm (more )
Structure Level Pattern Image Note
TS19: inner ear Present Regionally restricted 5K Expression was in dorsolateral inner ear.
Specimen 5L: embryonic day 11.5; Chd7Gt(S20-7E1)Sor/Chd7tm1.1Dmm, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: inner ear Absent 5L
Specimen Table 1 +/+ E10.5: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: inner ear Present
Specimen Table 1 Gt/+ E10.5: embryonic day 10.5; Chd7Gt(S20-7E1)Sor/Chd7+ (more )
Structure Level Pattern Image Note
TS17: inner ear Present
Specimen Table 1 Gt/Gt E10.5: embryonic day 10.5; Chd7Gt(S20-7E1)Sor/Chd7Gt(S20-7E1)Sor (more )
Structure Level Pattern Image Note
TS17: inner ear Absent
Specimen Table 1 Cond. het E10.5: embryonic day 10.5; Chd7tm1.1Dmm/Chd7+, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: inner ear Present
Specimen Table 1 CKO E10.5: embryonic day 10.5; Chd7Gt(S20-7E1)Sor/Chd7tm1.1Dmm, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: inner ear Weak Expression was reduced.
Specimen Table 1 +/+ E11.5: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: inner ear Present
Specimen Table 1 Gt/+ E11.5: embryonic day 11.5; Chd7Gt(S20-7E1)Sor/Chd7+ (more )
Structure Level Pattern Image Note
TS19: inner ear Present
Specimen Table 1 Cond. het E11.5: embryonic day 11.5; Chd7tm1.1Dmm/Chd7+, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: inner ear Present
Specimen Table 1 CKO E11.5: embryonic day 11.5; Chd7Gt(S20-7E1)Sor/Chd7tm1.1Dmm, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: inner ear Absent
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory