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Gene Expression Data
Assay Details
Assay
Reference: J:188806 Hurd EA, et al., Delayed fusion and altered gene expression contribute to semicircular canal defects in Chd7 deficient mice. Mech Dev. 2012 Sep;129(9-12):308-23
Assay type: RNA in situ
MGI Accession ID: MGI:6305130
Gene symbol: Lmx1a
Gene name: LIM homeobox transcription factor 1 alpha
Probe: Lmx1a probe7
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 3A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: otocyst Present Regionally restricted 3A Expression was detected in dorsal otocyst.
Specimen 3B: embryonic day 10.5; Chd7Gt(S20-7E1)Sor/Chd7+ (more )
Structure Level Pattern Image Note
TS17: otocyst Present Regionally restricted 3B Expression was detected in dorsal otocyst.
Specimen 3C: embryonic day 10.5; Chd7Gt(S20-7E1)Sor/Chd7Gt(S20-7E1)Sor (more )
Structure Level Pattern Image Note
TS17: otocyst Present Regionally restricted 3C Expression was detected in dorsal otocyst, as in wild type.
Specimen 3D: embryonic day 10.5; Chd7tm1.1Dmm/Chd7+, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: otocyst Present Regionally restricted 3D Expression was detected in dorsal otocyst, as in wild type.
Specimen 3E: embryonic day 10.5; Chd7Gt(S20-7E1)Sor/Chd7tm1.1Dmm, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: otocyst Present Regionally restricted 3E Expression was detected in dorsal otocyst, as in wild type.
Specimen 5A: embryonic day 11.5; Chd7tm1.1Dmm/Chd7+ (more )
Structure Level Pattern Image Note
TS19: inner ear Present Regionally restricted 5A Expression was in dorsomedial inner ear.
Specimen 5B: embryonic day 11.5; Chd7tm1.1Dmm/Chd7+, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: inner ear Present Regionally restricted 5B Expression was in dorsomedial inner ear.
Specimen 5C: embryonic day 11.5; Chd7Gt(S20-7E1)Sor/Chd7tm1.1Dmm (more )
Structure Level Pattern Image Note
TS19: inner ear Present Regionally restricted 5C Expression was in dorsomedial inner ear.
Specimen 5D: embryonic day 11.5; Chd7Gt(S20-7E1)Sor/Chd7tm1.1Dmm, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: inner ear Present Regionally restricted 5D Expression was preserved in the conditional mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory