Tg(Thy1-Nrg1)FLMhsb
Transgene Detail
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| Symbol: |
Tg(Thy1-Nrg1)FLMhsb |
| Name: |
transgene insertion FL, Markus H Schwab |
| MGI ID: |
MGI:6303795 |
| Synonyms: |
HA-NRG1FL |
| Transgene: |
Tg(Thy1-Nrg1)FLMhsb Location: unknown
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| Alliance: |
Tg(Thy1-Nrg1)FLMhsb page
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| Transgene Type: |
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Transgenic (Epitope tag, Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(Thy1-Nrg1)FLMhsb expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Note |
| mouse |
Nrg1 (MGI:96083) |
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Mutation details: A mouse Nrg1 type IIIb1a cDNA, plus sequence for two hemagglutinin (HA) peptide tags inserted immediately after the ATG start codon, was placed downstream of the Thy1 promoter. This vector contains the entire Thy1 gene (including 5' promoter and 3' polyA signal sequences and neuronal-specific expression signal containing introns) with the coding region removed (from the ATG in exon 2 to the end in exon 4, including intervening introns 2 and 3). Nrg1 sequence was inserted between the remaining sequences of Thy1 exons 2 and 4. The transgene was injected into fertilized FVB oocytes.
(J:262505)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:262505 Velanac V, et al., Bace1 processing of NRG1 type III produces a myelin-inducing signal but is not essential for the stimulation of myelination. Glia. 2012 Feb;60(2):203-17 |
| All: |
4 reference(s) |
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Analysis Tools
