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Gene Expression Data
Assay Details
Assay
Reference: J:200762 Buttler K, et al., Maldevelopment of dermal lymphatics in Wnt5a-knockout-mice. Dev Biol. 2013 Sep 15;381(2):365-76
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6296745
Gene symbol: Prox1
Gene name: prospero homeobox 1
Antibody: anti-Prox1
Detection system: Alexa Fluor 488
Results
Specimen 2B: embryonic day 18.5 (more )
Note: Triple labeled: red - Prox1; green - Wnt5a (assay MGI:6296744); blue - Dapi.
Structure Level Pattern Image Note
TS26: dermis Present Regionally restricted 2B
TS26: lymphatic vessel Present Regionally restricted 2B
Specimen 7G: embryonic day 18.5; Wnt5atm1Amc/Wnt5atm1Amc (more )
Note: Triple labeled: red - Prox1; green - CD31 (Pecam1 assay MGI:6296746); blue - Dapi.
Structure Level Pattern Image Note
TS26: dermis Present Regionally restricted 7G Expression in dermis of dorsal thoracic region.
TS26: lymphatic vessel Present Regionally restricted 7G Co-expression with Pecam1 in lymphatics with large lumen.
Specimen 8C: embryonic day 18.5; Wnt5atm1Amc/Wnt5a+ (more )
Note: Triple labeled: red - Prox1; green - CD31 (Pecam1 assay MGI:6296746); blue - Dapi.
Structure Level Pattern Image Note
TS26: dermis Present Regionally restricted 8C Expression in dermis of abdominal region.
TS26: lymphatic vessel Present Regionally restricted 8C Expression in nucleus. Authors report a regular pattern of initial lymphatics in heterozygous mutant embryos.
Specimen 8D: embryonic day 18.5; Wnt5atm1Amc/Wnt5atm1Amc (more )
Note: Triple labeled: red - Prox1; green - CD31 (Pecam1 assay MGI:6296746); blue - Dapi.
Structure Level Pattern Image Note
TS26: dermis Present Regionally restricted 8D Expression in dermis of abdominal region.
TS26: lymphatic vessel Present Regionally restricted 8D Authors report expression in huge but irregularly distributed lymphatics in homozygous mutant embryos.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
MGI 6.23 		The Jackson Laboratory