Gene Expression Data
Assay Details
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Assay
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Reference:
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J:56236
Dickman ED, et al., Abnormal skeletogenesis occurs coincident with increased apoptosis in the Splotch (Sp2H) mutant: putative roles for Pax3 and PDGFRalpha in rib patterning. Anat Rec. 1999 Jul 1;255(3):353-61
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:6295974
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Gene symbol:
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Pdgfra
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Gene name:
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platelet derived growth factor receptor, alpha polypeptide
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Results
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Specimen
2h wild type:
embryonic day 10.0
(more  )
Specimen
2h wild type:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 10.0
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS16: somite |
Present |
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2h wild-type
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Specimen
2h Splotch:
(close )
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Genetic Background:
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involves: 101 * C3H/He
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Mutant Allele(s):
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Pax3Sp-2H/Pax3Sp-2H
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Age:
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embryonic day 10.0
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS16: somite |
Present |
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2h Splotch
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At E10.0, Splotch embryos displayed normal spatial localization of Pdgfra transcripts.
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Specimen
2i wild type:
embryonic day 12.5
(more )
Specimen
2i wild type:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: somite |
Present |
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2i wild-type
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Specimen
2i Splotch:
(close )
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Genetic Background:
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involves: 101 * C3H/He
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Mutant Allele(s):
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Pax3Sp-2H/Pax3Sp-2H
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: somite |
Weak |
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2i Splotch
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By E12.5, Pdgfra expression was severely decreased in the thoracic somite region and ventrally truncated.
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Analysis Tools