Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(Prnp-MAPT*P130L)23027Shoj
Name:	transgene insertion 23207, Mikio Shoji
MGI ID:	MGI:6295463
Synonyms:	FTDP-17, TgTauP301L, TgTau(P301L)23027
Transgene:	Tg(Prnp-MAPT*P130L)23027Shoj  Location: unknown
Alliance:	Tg(Prnp-MAPT*P130L)23027Shoj page

Strain of Origin:

(129S1/Sv FVB/N)F1

Transgene Type:    Transgenic (Inserted expressed sequence) Mutation:    Insertion   Mutation details: The longest isoform of human 2N4R wild-type (wt) tau (MAPT) cDNA containing a eukaryotic Kozak initiation sequence upstream of the start codon was ligated to the SalI-digested site of a linearized cos- Tet expression vector containing the Syrian hamster prion protein gene promoter. (J:113391)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:113391 Murakami T, et al., Cortical neuronal and glial pathology in TgTauP301L transgenic mice: neuronal degeneration, memory disturbance, and phenotypic variation. Am J Pathol. 2006 Oct;169(4):1365-75
All:	12 reference(s)