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Gene Expression Data
Assay Details
Assay
Reference: J:82121 Luque JM, et al., Localization of ApoER2, VLDLR and Dab1 in radial glia: groundwork for a new model of reelin action during cortical development. Brain Res Dev Brain Res. 2003 Feb 16;140(2):195-203
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6295389
Gene symbol: Dab1
Gene name: disabled 1
Antibody: anti-mDab1 B3
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 3A: embryonic day 15.5 (more )
Note: Double labeled: green - Dab1; red - Nes (assay MGI:6295390).
Structure Level Pattern Image Note
TS23: cerebral cortex ventricular layer Present 3C , 3A Co-localization of staining with Nestin was noted. Expression was present in radial glia and their processes.
Specimen 4C: embryonic day 14.5 (more )
Note: Double labeled: green - Dab1; red - Nes (assay MGI:6295390).
Structure Level Pattern Image Note
TS22: cerebral cortex ventricular layer Present 4C , 4G
TS22: neocortex Present Regionally restricted 4C , 4G In wild type there was a partial localization of Dab1 staining in Nestin-positive radial end-feet.
Specimen 4D: embryonic day 14.5; Relnrl-Orl/Relnrl-Orl (more )
Note: Double labeled: green - Dab1; red - Nes (assay MGI:6295390).
Structure Level Pattern Image Note
TS22: cerebral cortex ventricular layer Weak 4H , 4D
TS22: neocortex Present Regionally restricted 4H , 4D Dab1 signal accumulated in Nestin-positive radial end-feet beneath the pia matter in the mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory