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Gene Expression Data
Assay Details
Assay
Reference: J:26500 Schmitt I, et al., Expression of the Huntington disease gene in rodents: cloning the rat homologue and evidence for downregulation in non-neuronal tissues during development. Hum Mol Genet. 1995 Jul;4(7):1173-82
Assay type: RNA in situ
MGI Accession ID: MGI:6295158
Gene symbol: Htt
Gene name: huntingtin
Probe: Rhd5 probe
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 6a/b: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: diencephalon Strong 6a/b Strong, highly specific expression within all neuronal tissue - telencephalon, diencephalon including neurohypophysis, down to spinal cord and spinal ganglia.
TS20: medulla oblongata Strong 6a/b Strong, highly specific expression within all neuronal tissue - telencephalon, diencephalon including neurohypophysis, down to spinal cord and spinal ganglia.
TS20: midbrain Strong 6a/b Strong, highly specific expression within all neuronal tissue - telencephalon, diencephalon including neurohypophysis, down to spinal cord and spinal ganglia.
TS20: neurohypophysis Strong 6a/b Strong, highly specific expression within all neuronal tissue - telencephalon, diencephalon including neurohypophysis, down to spinal cord and spinal ganglia.
TS20: spinal cord Strong 6a/b Strong, highly specific expression within all neuronal tissue - telencephalon, diencephalon including neurohypophysis, down to spinal cord and spinal ganglia.
TS20: spinal ganglion Strong 6a/b Strong, highly specific expression within all neuronal tissue - telencephalon, diencephalon including neurohypophysis, down to spinal cord and spinal ganglia.
TS20: telencephalon Strong 6a/b Strong, highly specific expression within all neuronal tissue - telencephalon, diencephalon including neurohypophysis, down to spinal cord and spinal ganglia.

Specimen 7a/b: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: metencephalon Strong 7a/b High and specific expression in all neuronal tissues, predominantly is central nervous system (telencephalon, mesencephalon, metencephalon).
TS22: midbrain Strong 7a/b High and specific expression in all neuronal tissues, predominantly is central nervous system (telencephalon, mesencephalon, metencephalon).
TS22: telencephalon Strong 7a/b High and specific expression in all neuronal tissues, predominantly is central nervous system (telencephalon, mesencephalon, metencephalon).
TS22: peripheral nervous system Present 7a/b
TS22: retina Present 7a/b
TS22: spinal ganglion Present 7a/b
TS22: trigeminal ganglion Present 7a/b

Specimen 8a/b: postnatal day 2 (more )
Structure Level Pattern Image Note
TS27: brain Strong 8a/b Expression becomes more pronounced and more specific for brain.

Specimen 8c/d: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: dentate gyrus Strong 8c/d
TS28: hippocampus pyramidal cell layer Strong 8c/d

Specimen 9a/b: postnatal adult (more )
Structure Level Pattern Image Note
TS28: dentate gyrus Strong 9a/b
TS28: hippocampus pyramidal cell layer Strong 9a/b

Specimen 9c/d: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Present Regionally restricted 9c/d Within cerebral cortex, expression declines and is restricted to single neuronal cells of granular layer.

Specimen 9e/f: postnatal adult (more )
Structure Level Pattern Image Note
TS28: retina inner nuclear layer Present 9e/f Expression in retina predominantly in inner neuroblastic layer.

Specimen 9g/h: postnatal adult (more )
Structure Level Pattern Image Note
TS28: olfactory epithelium Present 9g/h Expression within nasal cavity restricted to olfactory epithelium.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory