Tg(Prnp-MFN1)1Balo Transgene Detail MGI Mouse (MGI:6295149)

Tg(Prnp-MFN1)1Balo
Transgene Detail

Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Summary

Symbol:	Tg(Prnp-MFN1)1Balo
Name:	transgene insertion 1, Robert Baloh
MGI ID:	MGI:6295149
Synonyms:	Prp-MFN1
Transgene:	Tg(Prnp-MFN1)1Balo Location: unknown
Alliance:	Tg(Prnp-MFN1)1Balo page

Transgene
origin

Strain of Origin:

C57BL/6J

Transgene
description

Transgene Type:

Transgenic (Epitope tag, Humanized sequence, Inserted expressed sequence)

Mutation:

Insertion

Tg(Prnp-MFN1)1Balo expresses 1 gene

Mutation details: The 14303 bp transgenic construct is designed to contain a murine prion protein (Prnp) promoter driving expression of a flag-tagged human mitofusin 1 (MFN1) gene. (J:273854)

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

Original:	J:273854 Zhou Y, et al., Restoring mitofusin balance prevents axonal degeneration in a Charcot-Marie-Tooth type 2A model. J Clin Invest. 2019 Mar 18;130:1756-1771
All:	2 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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