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Gene Expression Data
Assay Details
Assay
Reference: J:199592 Yang L, et al., ESET histone methyltransferase is essential to hypertrophic differentiation of growth plate chondrocytes and formation of epiphyseal plates. Dev Biol. 2013 Aug 1;380(1):99-110
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6294698
Gene symbol: Setdb1
Gene name: SET domain, bifurcated 1
Antibody: anti-Setdb1 (07-378)
Detection system: Cy3
Results
Specimen E17.5 WT not shown: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: epiphyseal plate Present Regionally restricted Authors report transient upregulation of expression within prehypertrophic regions in long bone growth plates from E17.5 and E18.5 embryos.
Specimen E18.5 WT not shown: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: epiphyseal plate Present Regionally restricted Authors report transient upregulation of expression within prehypertrophic regions in long bone growth plates from E17.5 and E18.5 embryos.
Specimen 1c WT: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: tibia Present Regionally restricted 1c Anti-ESET WT Authors report transient upregulation of expression in prehypertrophic chondrocytes in wildtype proximal tibia.
Specimen 1c CKO/CKO: postnatal newborn; Setdb1tm1.1Yshk/Setdb1tm1.1Yshk, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: tibia Absent 1c Anti-ESET CKO/CKO No expression in proximal tibia of mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory