Gene Expression Data
Assay Details
Assay
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Reference:
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J:24148
Mitsiadis TA, et al., Midkine (MK), a heparin-binding growth/differentiation factor, is regulated by retinoic acid and epithelial-mesenchymal interactions in the developing mouse tooth, and affects cell proliferation and morphogenesis. J Cell Biol. 1995 Apr;129(1):267-81
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:6294285
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Gene symbol:
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Mdk
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Gene name:
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midkine
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Results
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Specimen
2a:
embryonic day 11.5
(more )
Specimen
2a:
(close )
Genetic Background:
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either: (C57BL * CBA) or (CBA * NMRI)
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Age:
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embryonic day 11.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
2b:
embryonic day 13.5
(more )
Note: Bud stage of tooth development.
Specimen
2b:
(close )
Genetic Background:
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either: (C57BL * CBA) or (CBA * NMRI)
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Age:
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embryonic day 13.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Note:
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Bud stage of tooth development.
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Structure |
Level |
Pattern |
Image |
Note |
TS21: lower jaw molar epithelium |
Present |
Regionally restricted |
2b
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Expression is on the cell surface of the dental epithelial bud and in the basement membrane.
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TS21: tooth bud |
Present |
Regionally restricted |
2b
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Expression is on the cell surface of the dental epithelial bud and in the basement membrane.
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TS21: lower jaw molar mesenchyme |
Present |
Regionally restricted |
2b
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Expression is on the cell surface of the condensed dental mesenchyme.
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Specimen
2c:
embryonic day 14.5
(more )
Note: Early cap stage of tooth development.
Specimen
2c:
(close )
Genetic Background:
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either: (C57BL * CBA) or (CBA * NMRI)
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Age:
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embryonic day 14.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
|
4% Paraformaldehyde
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Embedding:
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Paraffin
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Note:
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Early cap stage of tooth development.
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Structure |
Level |
Pattern |
Image |
Note |
TS22: lower jaw molar mesenchyme |
Present |
Regionally restricted |
2c
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Expression is on the cell surface of the condensed dental mesenchyme.
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TS22: lower jaw molar epithelium |
Present |
Regionally restricted |
2c
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Expression is on the cell surface of the dental epithelial bud and in the basement membrane.
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TS22: lower jaw |
Present |
Regionally restricted |
2c
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Expression is in the dental epithelium and mesenchyme and is absent in surrounding tissues.
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TS22: mandible |
Weak |
Regionally restricted |
2c
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Expression is in osteogenic and chondrogenic areas.
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TS22: cap stage tooth |
Present |
Regionally restricted |
2c
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Specimen
2d:
embryonic day 16.5
(more )
Note: Early bell stage of tooth development.
Specimen
2d:
(close )
Genetic Background:
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either: (C57BL * CBA) or (CBA * NMRI)
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Age:
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embryonic day 16.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Note:
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Early bell stage of tooth development.
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Specimen
2e:
embryonic day 18.5
(more )
Note: Bell stage of tooth development.
Specimen
2e:
(close )
Genetic Background:
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either: (C57BL * CBA) or (CBA * NMRI)
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Age:
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embryonic day 18.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Note:
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Bell stage of tooth development.
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Specimen
2f:
postnatal day 1
(more )
Specimen
2f:
(close )
Genetic Background:
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either: (C57BL * CBA) or (CBA * NMRI)
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Age:
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postnatal day 1
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
3b:
embryonic day 15.5
(more )
Note: Cap stage of tooth development.
Specimen
3b:
(close )
Genetic Background:
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either: (C57BL * CBA) or (CBA * NMRI)
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Age:
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embryonic day 15.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Note:
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Cap stage of tooth development.
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Specimen
not shown:
embryonic day 12.5
(more )
Specimen
not shown:
(close )
Genetic Background:
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either: (C57BL * CBA) or (CBA * NMRI)
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Age:
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embryonic day 12.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Structure |
Level |
Pattern |
Image |
Note |
TS20: oral region mesenchyme |
Present |
Regionally restricted |
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Expression is on the surfaces of condensing mesenchymal cells in close contact with dental epithelium and is punctate in more peripheral mesenchymal cells.
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