Rr94tm1.2Itan
Targeted Allele Detail
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| Symbol: |
Rr94tm1.2Itan |
| Name: |
regulatory region 94; targeted mutation 1.2, Ichiro Taniuchi |
| MGI ID: |
MGI:6294091 |
| Synonyms: |
Cd4deltaE4p, Cd4tm1.2Itan |
| Gene: |
Rr94 Location: unknown Genetic Position: Chr6, Syntenic
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| Alliance: |
Rr94tm1.2Itan page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:267930
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| Parent Cell Line: |
M1/M-1 (ES Cell)
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| Strain of Origin: |
(129 x C57BL/6)F1
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| Allele Type: |
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Targeted (Modified regulatory region) |
| Mutations: |
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Insertion, Intragenic deletion
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Mutation details: A floxed synthesized Eth enhancer composed of the DNA core enhancer sequences from the Thpok thymic enhancer (TE) and the proximal enhancer (PE) replaced the 430 bp Cd4 proximal enhancer (E4p). Cre-mediated recombination removed the selection cassette and Eth enhancer.
(J:267930)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Rr94 Mutation: |
0 strains or lines available
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| Original: |
J:267930 Kojo S, et al., Runx-dependent and silencer-independent repression of a maturation enhancer in the Cd4 gene. Nat Commun. 2018 Sep 5;9(1):3593 |
| All: |
1 reference(s) |
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Analysis Tools
