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Gene Expression Data
Assay Details
Assay
Reference: J:266589 Cohen-Tayar Y, et al., Pax6 regulation of Sox9 in the mouse retinal pigmented epithelium controls its timely differentiation and choroid vasculature development. Development. 2018 Aug 9;145(15):dev163691
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6293891
Gene symbol: Sox9
Gene name: SRY (sex determining region Y)-box 9
Antibody: Anti-Sox9 (AB5535)
Detection system: Secondary antibody coupled to Alexa Fluor 594
Results
Specimen 1A: embryonic day 15.5 (more )
Note: Double labeled: red - Sox9; green - Pax6 (assay MGI:6293892).
Structure Level Pattern Image Note
TS23: pigmented retinal epithelium Present 1A
Specimen 2A: embryonic day 13.5; Sox9tm2Crm/Sox9tm2Crm (more )
Note: Double labeled: red - Sox9; green - Pax6 (assay MGI:6293892).
Structure Level Pattern Image Note
TS21: pigmented retinal epithelium Present 2A
Specimen 2B: embryonic day 13.5; Sox9tm2Crm/Sox9tm2Crm, Tg(Dct-cre)1Apdn/0 (more )
Note: Conditional mutant. Double labeled: red - Sox9; green - Pax6 (assay MGI:6293892).
Structure Level Pattern Image Note
TS21: pigmented retinal epithelium Absent 2B
Specimen S1J: embryonic day 13.5 (more )
Note: Double labeled: red - Sox9; green - Pax6 (assay MGI:6293892).
Structure Level Pattern Image Note
TS21: pigmented retinal epithelium Present Regionally restricted S1B , S1J Expression initially appeared near the optic nerve head.
Specimen S1K: embryonic day 15.5 (more )
Note: Double labeled: red - Sox9; green - Pax6 (assay MGI:6293892).
Structure Level Pattern Image Note
TS23: pigmented retinal epithelium Present S1K , S1C
Specimen S1L: embryonic day 19.5 (more )
Note: Double labeled: red - Sox9; green - Pax6 (assay MGI:6293892).
Structure Level Pattern Image Note
TS26: pigmented retinal epithelium Present S1L , S1D
Specimen S1M: postnatal day 8 (more )
Note: Double labeled: red - Sox9; green - Pax6 (assay MGI:6293892).
Structure Level Pattern Image Note
TS28: pigmented retinal epithelium Present S1E , S1M Expression eventually reached the optic cup periphery.
Specimen S2A/C: embryonic day 13.5; Pax6tm2Pgr/Pax6tm2Pgr (more )
Note: Double labeled: red - Sox9; green - Pax6 (assay MGI:6293892).
Structure Level Pattern Image Note
TS21: pigmented retinal epithelium Present S2A , S2A' , S2C' , S2C
Specimen S2D/F: embryonic day 13.5; Pax6tm2Pgr/Pax6tm2Pgr (more )
Note: Conditional mutant. Double labeled: red - Sox9; green - Pax6 (assay MGI:6293892).
Structure Level Pattern Image Note
TS21: pigmented retinal epithelium Present Non-Uniform S2D' , S2F , S2F' , S2D Expression was increased in the peripheral retinal pigmented epithelium of the Pax6 cKO compared to control.
Specimen S4A/C: embryonic day 13.5; Sox9tm2Crm/Sox9tm2Crm (more )
Note: Double labeled: red - Sox9; green - Pax6 (assay MGI:6293892).
Structure Level Pattern Image Note
TS21: pigmented retinal epithelium Present S4C' , S4A , S4C , S4A'
Specimen S4D/F: embryonic day 13.5; Sox9tm2Crm/Sox9tm2Crm, Tg(Dct-cre)1Apdn/0 (more )
Note: Conditional mutant. Double labeled: red - Sox9; green - Pax6 (assay MGI:6293892).
Structure Level Pattern Image Note
TS21: pigmented retinal epithelium Absent S4D , S4F' , S4F , S4D'
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory