Gene Expression Data
Assay Details
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Assay
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Reference:
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J:187511
Besser M, et al., Tenascin C regulates proliferation and differentiation processes during embryonic retinogenesis and modulates the de-differentiation capacity of Muller glia by influencing growth factor responsiveness and the extracellular matrix compartment. Dev Biol. 2012 Sep 15;369(2):163-76
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:6287954
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Gene symbol:
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Ptprz1
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Gene name:
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protein tyrosine phosphatase receptor type Z, polypeptide 1
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Antibody:
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473HD
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Detection system:
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Cy3
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Results
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Specimen
7a:
embryonic day 13.5
(more  )
Specimen
7a:
(close  )
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Genetic Background:
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129
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: neural retina |
Present |
Regionally restricted |
7a
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Expresssion initially concentrated in the inner neuroblastic layer.
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Specimen
7b:
(close )
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Genetic Background:
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involves: 129S2/SvPas
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Mutant Allele(s):
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Tnctm1Ref/Tnctm1Ref
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
7c:
embryonic day 15.5
(more )
Specimen
7c:
(close )
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Genetic Background:
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129
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS23: neural retina |
Present |
Regionally restricted |
7c
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Expansion of expression towards the inner plexiform layer.
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Specimen
7d:
(close )
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Genetic Background:
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involves: 129S2/SvPas
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Mutant Allele(s):
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Tnctm1Ref/Tnctm1Ref
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS23: neural retina |
Very strong |
Regionally restricted |
7d
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Authors report expression dramatically upregulated in mutant retinas, especially during E13.5 to E15.5. Increased expression in the outer most apical layer.
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Specimen
7e:
embryonic day 18.5
(more )
Specimen
7e:
(close )
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Genetic Background:
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129
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
7f:
(close )
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Genetic Background:
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involves: 129S2/SvPas
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Mutant Allele(s):
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Tnctm1Ref/Tnctm1Ref
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: neural retina |
Strong |
Regionally restricted |
7f
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Authors report expression dramatically upregulated in mutant retinas. Increased expression in the outer most apical layer.
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Analysis Tools