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Gene Expression Data
Assay Details
Assay
Reference: J:230953 De Maria A, et al., Birc7: A Late Fiber Gene of the Crystalline Lens. Invest Ophthalmol Vis Sci. 2015 Jul;56(8):4823-34
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6287747
Gene symbol: Birc7
Gene name: baculoviral IAP repeat-containing 7
Antibody: Anti-Livin
Assay notes: Two antibodies were described; the one used in this assay was not specified. Either MGI:6287697 or MGI:6287699 could have been used.
Results
Specimen 7A: postnatal day 1 (more )
Note: Vibratome section.
Structure Level Pattern Image Note
TS27: lens fiber Present 7A , 7C Expression was detected in inner cortical fiber cells that had recently detached from the lens epithelium. Expression was detected in fiber cells immediately prior to denucleation. Immunofluorescence was distributed throughout the cytoplasm.
Specimen 7B: postnatal day 1 (more )
Note: Vibratome section.
Structure Level Pattern Image Note
TS27: lens fiber Present Regionally restricted 7B Immunofluorescence formed an annular pattern in fiber cells in the inner cortical region.
Specimen 7D: postnatal day 1 (more )
Note: Vibratome section.
Structure Level Pattern Image Note
TS27: lens epithelium Absent 7D
Specimen S3 Birc7+/+: postnatal (more )
Structure Level Pattern Image Note
TS28: lens fiber Present Regionally restricted S3_left Expression was detected in nucleated fibers located in the deep cortical region.
Specimen S3 LeCretg/-;Birc7flox/flox: postnatal; Birc7tm1Sbss/Birc7tm1Sbss, Tg(Pax6-cre,GFP)1Pgr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: lens fiber Absent S3_center
Specimen S3 MLR10tg/-;Birc7flox/flox: postnatal; Birc7tm1Sbss/Birc7tm1Sbss, Tg(Cryaa-cre)10Mlr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: lens fiber Absent S3_right
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory