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Gene Expression Data
Assay Details
Assay
Reference: J:28253 Tureckova J, et al., Comparison of expression of the msx-1, msx-2, BMP-2 and BMP-4 genes in the mouse upper diastemal and molar tooth primordia. Int J Dev Biol. 1995 Jun;39(3):459-68
Assay type: RNA in situ
MGI Accession ID: MGI:6286388
Gene symbol: Msx2
Gene name: msh homeobox 2
Probe: p-lambda-26
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 2A/B: embryonic day 11.0 (more )
Note: Embryonic age is 10 days and 20 hours.
Structure Level Pattern Image Note
TS18: oral epithelium Present Regionally restricted 2A/B Expression is in the epithelial thickening in the diastema region and is missing in the molar region.
TS18: 1st branchial arch maxillary component ectoderm Present Diffuse 2A/B Expression is in the mesial pole.
TS18: 1st branchial arch maxillary component mesenchyme Present Diffuse 2A/B Expression is in the mesial pole.
TS18: 1st branchial arch maxillary component Present Regionally restricted 2A/B Expression is at the buccal part of the diastemal epithelial thickening and in the adjacent mesenchyme and progressed as far as the facial surface.

Specimen 2C/D: embryonic day 11.0 (more )
Note: Embryonic age is 10 days and 20 hours.
Structure Level Pattern Image Note
TS18: oral epithelium Present Regionally restricted 2C/D Expression is in the epithelial thickening in the molar region and is missing in the diastema region.
TS18: oral region Present Regionally restricted 2C/D There is mesenchymal expression above the buccal part of the molar epithelial thickening which progresses into the upper lip or cheek throughout the whole mesio-distal course of the molar anlage.

Specimen 2E/F: embryonic day 12.0 (more )
Note: Embryonic age is 11 days and 20 hours.
Structure Level Pattern Image Note
TS20: oral epithelium Present Regionally restricted 2E/F Expression is in the molar region and is missing in the diastema region.
TS20: oral region Weak Regionally restricted 2E/F There is weak mesenchymal expression above the lip furrow epithelium.
TS20: upper lip Weak Regionally restricted 2E/F There is weak mesenchymal expression.

Specimen 2G/H: embryonic day 12.0 (more )
Note: Embryonic age is 11 days and 20 hours.
Structure Level Pattern Image Note
TS20: oral epithelium Present Regionally restricted 2G/H Expression is in the molar region and is missing in the diastema region.

Specimen 2I/J: embryonic day 13.5 (more )
Note: Embryonic age is 13 days and 8 hours.
Structure Level Pattern Image Note
TS21: oral epithelium Present Regionally restricted 2I/J Expression is in the molar region and is missing in the diastema region.
TS21: upper lip skin Present Regionally restricted 2I/J Expression is in the epithelium of the lip furrow and the oral surface of the lip.
TS21: upper jaw molar epithelium Present Regionally restricted 2I/J Expression is in the buccal side of the mesial part of the molar anlage.
TS21: upper jaw molar mesenchyme Present Regionally restricted 2I/J Expression is around the dental lamina.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory