Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Nxph4em1(cre)Zak
Name:	neurexophilin 4; endonuclease-mediated mutation 1, Zachary Knight
MGI ID:	MGI:6285704
Synonyms:	Nxph4-2a-cre
Gene:	Nxph4  Location: Chr10:127361342-127370428 bp, - strand  Genetic Position: Chr10, 74.51 cM
Alliance:	Nxph4em1(cre)Zak page

Strain of Origin:

FVB/N

Allele Type:    Endonuclease-mediated (Recombinase) Mutation:    Insertion   Nxph4em1(cre)Zak expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Nxph4 (MGI:1336197)   Mutation details: CRISPR/Cas9 was used to insert T2A-Cre sequence immediately upstream of the endogenous Nxph4 stop codon. The mutation was created in FVB/N mice. (J:272756)

Activity:	Tissue activity of this recombinase allele
Driver:	Nxph4 (mouse) Summary of all recombinase alleles driven by Nxph4. Comparative matrix view of recombinase activities Alliance mouse Nxph4 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Nxph4 Mutation:	24 strains or lines available

Original:	J:272756 Zimmerman CA, et al., A gut-to-brain signal of fluid osmolarity controls thirst satiation. Nature. 2019 Mar 27;
All:	1 reference(s)