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Gene Expression Data
Assay Details
Assay
Reference: J:267268 Huang H, et al., Interactive Repression of MYRF Self-Cleavage and Activity in Oligodendrocyte Differentiation by TMEM98 Protein. J Neurosci. 2018 Nov 14;38(46):9829-9839
Assay type: RNA in situ
MGI Accession ID: MGI:6285631
Gene symbol: Tmem98
Gene name: transmembrane protein 98
Probe: Tmem98 cDNA1
Probe preparation: Antisense RNA
Results
Specimen 1A: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: spinal cord white matter Present Regionally restricted 1A Expressed in the ventral white matter.
Specimen 1B: postnatal day 4 (more )
Structure Level Pattern Image Note
TS28: spinal cord Present 1B Increased expression.
Specimen 1C: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: spinal cord Present 1C Increased expression. Highest expression.
Specimen 1D: postnatal day 15 (more )
Structure Level Pattern Image Note
TS28: spinal cord gray matter Present 1D
TS28: spinal cord white matter Present 1D
Specimen 1E: postnatal day 15 (more )
Structure Level Pattern Image Note
TS28: corpus callosum Present 1E
Specimen 1F: postnatal day 15 (more )
Structure Level Pattern Image Note
TS28: cerebellum white matter Present 1F
Specimen 2A/B: postnatal day 7 (more )
Note: Double labeled: blue - Tmem98; brown - Sox10 (assay MGI:6285643).
Structure Level Pattern Image Note
TS28: spinal cord Present 2B , 2A Mostly coexpressed with the Sox10, which expressed in oligodendrocyte progenitor cells and mature oligodendrocytes.
Specimen 2C/D: postnatal day 7 (more )
Note: Double labeled: blue - Tmem98; brown - Apc (assay MGI:6285644).
Structure Level Pattern Image Note
TS28: spinal cord Present 2C , 2D Mostly coexpressed with Apc, which expressed in the young differentiated oligodendrocytes.
Specimen 2E/F: postnatal day 7 (more )
Note: Double labeled: blue - Tmem98; brown - Myrf (assay MGI:6285645).
Structure Level Pattern Image Note
TS28: spinal cord Present 2F , 2E Mostly coexpressed with Myrf, which expressed in postmitotic myelinating oligodendrocytes.
Specimen 2G/I: postnatal day 7 (more )
Note: Double labeled: blue - Tmem98; green - Pdgfra (assay MGI:6285646).
Structure Level Pattern Image Note
TS28: spinal cord Present 2I , 2G Not expressed in Pdgfra+ immature oligodendrocyte progenitor cells.
Specimen 2J: postnatal day 3; Nkx2-2tm5.1Suss/Nkx2-2+, Olig1tm1(cre)Rth/Olig1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: spinal cord Present 2J
Specimen 2K: postnatal day 3; Nkx2-2tm5.1Suss/Nkx2-2tm5.1Suss, Olig1tm1(cre)Rth/Olig1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: spinal cord Present 2K Severely decreased expression.
Specimen 2L: postnatal day 3; Myrftm1Barr/Myrf+, Olig1tm1(cre)Rth/Olig1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: spinal cord Present 2L
Specimen 2M: postnatal day 3; Myrftm1Barr/Myrftm1Barr, Olig1tm1(cre)Rth/Olig1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: spinal cord Present 2M Severely decreased expression.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory